Research on Molecular Chaperones: Role and Targeting in Health and Disease

Dear Colleagues,

We are pleased to invite you to submit original articles to a Special Issue entitled “Research on molecular chaperones: role and targeting in health and disease”.

Molecular chaperones, most of which are heat shock proteins (HSPs), are part of phylogenetically related families and are essential in living cells. Molecular chaperones play a variety of roles, including assisting the folding of nascent polypeptides, supporting protein reparation or degradation, and driving protein translocation through membranes. Chaperones are induced after stress, which changes their localization and function. For example, they can be expressed in cell membranes or secreted extracellularly where they may interact with the immune system.

Due to the central role of molecular chaperones in different biological processes, their dysregulation or malfunction may cause several diseases. The goal of this Special Issue is to collect original research papers, reviews that focus on the role of molecular chaperones in human diseases and highlight the diagnostic and therapeutic applications of these chaperones.

Dr. Antonella Marino Gammazza

Dr. Celeste Caruso Bavisotto

Guest Editors