Special Issue "Molecular Advances in Hypertension and Blood"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (28 March 2021) | Viewed by 5363
Interests: thrombotic microangiopathy; complement; complement inhibitors; hematopoietic cell transplantation; atypical hemolytic uremic syndrome; COVID-19; thrombotic thrombocytopenic purpura
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Interests: arterial hypertension; endothelial dysfunction; platelets; arterial stiffness; microvesicles; dipping; nitric oxide; cardiovascular risk
We are launching a Special Issue on “Molecular Advances in Hypertension and Blood”. Our Special Issue will address the topic from both sides of the coin.
Firstly, we plan to investigate the interesting and under-reported pathophysiology of hypertension in hematological oncology and hematopoietic cell transplantation. Although neglected, hypertension is not only a key diagnostic and prognostic clinical finding in acute syndromes, such as thrombotic microangiopathy, but also a late effect of long-term survivors leading to increased cardiovascular and cerebrovascular mortality. This Special Issue will cover molecular advances in this field, exploring the role of genetics and epigenetics components, the renin–angiotensin aldosterone system, the autonomous nervous system, as well as the role of the aging vascular tree and endothelium.
Secondly, hematopoietic cells and their microvesicles have recently emerged as novel markers of cardiovascular risk. The crosstalk between these vesicles and endothelial dysfunction or vascular damage is a field of continuous progress. Apart from being biomarkers, these could also pose promising therapeutic targets in the future. Thromboinflammation represents an emerging concept in cardiovascular diseases. Novel insights into the role of hematopoietic cells in hypertension will be covered in this Special Issue.
Realizing the unmet needs of increased awareness of treating physicians and active researchers in this complex setting, we propose this Special Issue. Since IJMS is a journal of molecular science, we will accept translational studies with biomolecular experiments. We hope that you will find it of interest and submit your valuable research.
Dr. Eleni Gavriilaki
Dr. Eugenia Gkaliagkousi
Manuscript Submission Information
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- arterial hypertension
- endothelial dysfunction
- thrombotic microangiopathy
- hematopoietic cell transplantation
- cardiovascular risk