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Special Issue "From hIPSCs to Adult Cells in a Dish: Promises and Pitfalls"
Deadline for manuscript submissions: closed (30 November 2019).
Human induced-pluripotent stem cells (hIPSCs) represent a source to produce a virtually unlimited number of cells from patients and healthy controls, which are otherwise difficult to obtain, such as, but not limited to, cardiomyocytes and neurons.
Cells derived from hIPSCs can be subsequently applied in preclinical and, possibly in the future, clinical studies such as target validation, drug screening, and tissue regeneration. However, IPSC-derived somatic cells often present significant differences from their adult counterparts in terms of maturity and gene expression.
This Special Issue of IJMS will cover, but will not be not limited to, the following topics:
- The success and limitations of hIPSC for disease modeling (including cardiac, neurological, liver, skin, blood diseases, and more)
- How to promote and evaluate the maturation of hiPSC-derived somatic cells
- hIPSCs to derive tissue and organ models
- The direct reprogramming of human somatic cells to bypass the generation of iPSC
You are warmly invited to submit original research and review articles related to any of these aspects.
Dr. Alessandra Rossini
Dr. Andrea Barbuti
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.