Gliomas: From Molecular Mechanisms to Therapeutic Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 18437
Special Issue Editors
Interests: pathology; molecular pathology; cytopathology; biomarkers of clinical interest in malignant pleural mesothelioma, colorectal carcinoma, lung cancer, malignant melanoma, thyroid tumours; viral carcinogenesis (polyomavirus and papillomavirus)
Special Issues, Collections and Topics in MDPI journals
2. Center for Autoimmune and Allergic Disease (CADD), Corso Trieste 15A, 28100 Novara, Italy
Interests: brain tumors; molecular genetics of solid tumors; cancer research; stem cells
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gliomas are the most frequent primary brain tumours; despite a multimodal therapeutic approach, based on surgery, radiotherapy and chemotherapy, their prognosis still remains poor. Thus, uncovering the underlying molecular mechanisms of glioma cancerogenesis could provide optional therapeutic strategies, leading to improvements in prognosis.
This Special Issue focuses on the pathogenetic mechanisms involved in the onset and progression of gliomas, in order to refine the existing algorithms in neuropathologic diagnosis and to establish appropriate management in neuro-oncological practice.
Potential topics include, but are not limited to, the following:
- Technical advancement in gold standard procedures (including magnetic resonance and positron emission tomography);
- Advances in the molecular genetics of gliomas by next-generation techniques with implications for classification and therapy;
- The tumour immune microenvironment and tumour heterogeneity in the discovery of new therapeutic biomarkers (i.e., tumour-associated antigens for CART-therapy);
- Introductions, in clinics, of novel therapeutic options (proton-therapy or immunotherapy).
This Special Issue is open to original contributions from experimental to clinical studies, including reports on improved experimental models and innovative therapies, describing the current advancement in the diagnosis and treatment of human gliomas.
Prof. Dr. Renzo Boldorini
Dr. Marta Mellai
Guest Editors
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