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Special Issue "Galectins in Cancer and Translational Medicine"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 November 2017).
A printed edition of this Special Issue is available here.
Prof. Dr. Armando Bartolazzi
1. Department of Pathology St. Andrea University Hospital, Rome, Italy; Undersecretary of State, Italian Ministry of Health;2. Cellular and Molecular Tumor Pathology Laboratory, Cancer Center Karolinska, Karolinska Hospital, Stockholm, Sweden.
Interests: tumor pathology; molecular pathology; cell biology; thyroid cancer; melanoma; solid tumors; molecular targeted therapy; monoclonal antibodies; immunochemistry; immunohistochemistry; galectins; CD44; integrins, adhesion molecules; cell–ECM interactions
Special Issues and Collections in MDPI journals
In the post-genomic era, many efforts have been devoted to better understand the biological information encoded by the cell “glycome” in normal and pathologic conditions. The glycan signature of human cells plays a pivotal role in regulating fundamental biological processes, which are critical for cell physiology and for cancer as well.
Galectins (also worded S-type lectins) are an evolutionarily conserved family of endogenous lectins, which bind carbohydrates with high specificity. These molecules, which can be found both intracellularly and in the extracellular milieu, are functionally active in converting glycan-containing information into cell biological programs. This fashionable mechanism of signal transduction plays a relevant role in regulating several biological functions, among which RNA splicing, gene transcription, cell migration and differentiation, apoptosis, immune response and tumor growth and progression.
It is not surprising, indeed, that a large number of studies on galectin–glycan interactions and galectins expression and function in human diseases have been published in the recent literature, spanning from immunology to cardiovascular medicine, from diagnostic Pathology to nuclear medicine.
The aim of this Special Issue of IJMS is to collect selected contributes in the field reporting data, concepts and new ideas, which have the potential to be translated in the clinical setting in a near future, in order to improve the diagnosis and treatment of cancer and other relevant human diseases.
Prof. Dr. Armando Bartolazzi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- galectins in diagnosis
- galectins in therapy
- galectins and immunity
- galectins and cancer
- galectins and human diseases