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Int. J. Mol. Sci. 2018, 19(4), 976; https://doi.org/10.3390/ijms19040976

Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications

1
Cardiology Department, Trousseau Hospital, François Rabelais University, 37000 Tours, France
2
Biochemistry Department, Trousseau Hospital, François Rabelais University, 37000 Tours, France
*
Author to whom correspondence should be addressed.
Received: 21 February 2018 / Revised: 15 March 2018 / Accepted: 23 March 2018 / Published: 25 March 2018
(This article belongs to the Special Issue Galectins in Cancer and Translational Medicine)
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Abstract

Maintenance of atrial fibrillation is a complex mechanism, including extensive electrical and structural remodeling of the atria which involves progressive fibrogenesis. Galectin-3 is a biomarker of fibrosis, and, thus, may be involved in atrial remodeling in atrial fibrillation patients. We review the role of galectin-3 in AF mechanisms and its potential therapeutic implications. View Full-Text
Keywords: galectin-3; atrial fibrillation; ablation galectin-3; atrial fibrillation; ablation
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Clementy, N.; Piver, E.; Bisson, A.; Andre, C.; Bernard, A.; Pierre, B.; Fauchier, L.; Babuty, D. Galectin-3 in Atrial Fibrillation: Mechanisms and Therapeutic Implications. Int. J. Mol. Sci. 2018, 19, 976.

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