Special Issue "Dry Eye and Ocular Surface Disorders"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 April 2017).
Interests: analytical (bio)chemistry; biochemistry, physiology, and pathophysiology of the ocular surface; chemistry, biochemistry, and biophysics of lipids; chemistry, biochemistry, and biophysics of the tear film and meibum; drug discovery; enzymology; meibomian gland studies
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Dry eye disease (DE) is a persistent, wide-spread, multifactorial disease that severely impacts the quality of life of people by impairing their vision, progresses with aging, and disproportionately affects women. In DE patients, the tear film—a protective layer that that covers the entire ocular surface – deteriorates and becomes unstable, losing its protective properties. There is evidence that DE is related to morphological changes in Meibomian glands (MG) and the chemical composition of MG secretions. Other known, highly relevant factors are the protein content of aqueous tears and their salinity. A delicate balance of all the components of the tear film is critical for maintaining a healthy ocular surface, and is altered in DE patients. This Special Issue of IJMS is seeking articles that would provide new insights into the underlying mechanisms of the onset of DE, the biochemistry and biophysics of the normal and DE tear film, new approaches to modelling and studying the condition, and new therapies and treatments for DE that would be able to alleviate or cure the disease.
Igor A. Butovich
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- Dry Eye
- Meibomian Gland
- Lacrimal Gland
- Lipids and Lipidomics
- Proteins and Proteomics
- Tear Film