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New Molecular Designs for Drugs including Potential Antibiotics

This special issue belongs to the section “Biochemistry“.

Special Issue Information

Dear Colleagues,

Living systems are the source of a diverse range of bioactive chemicals in many different ways. Naturally produced chemicals are of fundamental importance in biological systems and are used to mediate interactions across all levels of biological hierarchy. Natural products have also been the inspiration for semi-synthetic modifications, or as lead platforms for the synthesis of functional analogues targeted against specific receptors. Synthetic methodology allows the design and synthesis of completely new, yet active, “unnatural” structural types. Utilizing modern synthetic organic chemistry and “natural leads”, novel biologically active molecules can be developed for biological properties, including antimicrobial, anti-inflammatory and anticancer properties.

This Special Issue aims to cover a diverse range of synthetic and natural biologically active molecules for potential leads for drug discovery. Contributions from synthetic chemists, medicinal chemists, molecular biologists and pharmacologists are sought for this multi-disciplinary issue. In addition to manuscripts on the latest results, reviews are also encouraged.

Prof. Dr. David StC Black
Prof. Dr. Naresh Kumar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • design and synthesis of novel biologically active molecules
  • new targets for antibiotic discovery
  • structure based drug design
  • novel scaffolds for drug discovery
  • peptide mimics
  • cell-to-cell communication (e.g., quorum sensing)

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Int. J. Mol. Sci. - ISSN 1422-0067