Special Issue "Recent Advances in Antimicrobial Biomaterials"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: 31 May 2019
Biomaterial-related infection represents a significant public health issue and financial burden on governments and patients around the world. With the long-term overuse and misuse of antibiotics, the situation is likely to get worse in the future with the prevalence of antibiotic-resistant bacteria and increasing adoption of biomedical implants and devices. Antibiotics are no longer the magic bullets they were once thought to be, and, therefore, there is an urgent need for the development of antimicrobial biomaterials to prevent infections before they take hold. Antimicrobial biomaterials have been shown to reduce or prevent bacteria colonization on the biomaterial surface, either through physical, chemical, or biological interactions with the bacterial cell.
Several classes of antimicrobial biomaterials are discussed:
- Biomaterials that release antimicrobials
- Biomaterials where the antimicrobials are covalently attached
- Antifouling Biomaterials
- Biomaterials with nano-structured surfaces
Prof. Naresh Kumar
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access bimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Antimicrobial surfaces
- Antimicrobial coatings
- Bacterial colonization
- Antimicrobial biomaterials
- Infection control
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Author: Imran Rahim
Planned Title: Pseudomonas aeruginosa biofilm formation on magnesium implants and antibiotic resistance are dependent on inoculum.
Short abstract: Evaluation of novel antimicrobial strategies against biofilm infections requires characterization of infection dynamics. Previously established, here we investigate P. aeruginosa infection kinetics on magnesium implants to evaluate the efficacy of antimicrobials treatment. P. aeruginosa suspensions were injected at escalating infectious doses. Sequential in vivo imaging results revealed that the observed spatiotemporal kinetics of P. aeruginosa biofilms was dramatically influenced by the initial infectious dose. Antibiotic therapy success was inversely correlated to initial infectious dose. We posit that achieving a high density of suspended bacterial cells in the course of implant infections could play an essential role to establish long term survival.