Hormone Signaling in Human Health and Diseases 2.0
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 1270
Special Issue Editor
Interests: signal transduction; hormones; apoptosis; autophagy; metabolism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is a continuation of the 2022 Special Issue “Hormone Signaling in Human Health and Diseases”.
Cell signaling is part of any communication process that regulates the basic activities of cells and coordinates all cellular actions. The ability of cells to perceive and respond correctly to their microenvironment underlies the development, repair of tissues, immunity and homeostasis of normal tissues. Errors in signaling interactions and cellular information processing are responsible for three large classes of non-infectious diseases: cancers, neurodegenerative disorders and metabolic syndromes (such as type 2 diabetes and atherosclerosis). These diseases are remarkably complex and difficult to treat, primarily because when the cellular signaling pathways responsible for homeostasis and the health of the body become dysregulated, they generate similarly stable disease states.
Health- and disease-related conditions are dynamic and positively and negatively regulated by different feedback loops acting between pathways. Hormones are common signaling agents. Understanding cell signaling, especially relating hormone signaling, and describing regulatory networks in healthy and diseased states will show which molecular components may be the prime targets for drug interventions to manage these diseases more effectively. This is accomplished by studying models that explain in mechanistic, molecular detail the way in which a detailed part of the hormone signaling pathway functions properly in health and abnormally in disease.
Dr. Antonella Muscella
Guest Editor
Manuscript Submission Information
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Keywords
- hormone
- cell receptor
- endocrine signaling
- cancer
- insulin
- oestrogen
- testosterone
- angiotensin
- gonadotropin
- thyroid hormone
