Breast Cancer and Hormone Receptors: Molecular Insights
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 78
Special Issue Editors
Interests: breast cancer; medical oncology; molecular oncology
Interests: signal transduction; hormones; apoptosis; autophagy; metabolism
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hormone receptor-positive (HR+) breast cancer is the most common subtype. Advances in molecular profiling have revealed complex regulatory networks involving hormone receptor signaling, genomic instability, and immune modulation—shedding light on mechanisms of resistance and disease progression. A deeper understanding of these pathways is essential for refining therapeutic strategies and developing novel targeted interventions.
This Special Issue of IJMS, titled “Breast Cancer and Hormone Receptors: Molecular Insights”, invites original research articles, reviews, and short communications that explore the following:
- Molecular regulation and signaling of hormone receptors;
- Genomic and epigenetic factors influencing receptor expression;
- Biomarkers and predictive models for treatment response;
- Mechanisms of endocrine therapy resistance;
- Translational approaches linking molecular insights to clinical care.
By integrating perspectives from molecular oncology and clinical research, this issue aims to advance precision medicine in HR+ breast cancer and foster collaboration across disciplines.
Dr. Alkistis Papatheodoridi
Dr. Antonella Muscella
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- hormone receptor-positive breast cancer
- estrogen receptor (ER)
- progesterone receptor (PR)
- endocrine therapy resistance
- breast cancer genomics
- molecular biomarkers
- transcriptomic profiling
- targeted therapies
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