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Natural Polyphenols in Human Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 6

Special Issue Editor


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Guest Editor
Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez, Biochimica, Universita Politecnica delle Marche, Ancona, Italy
Interests: bioactive; inflammation; oxidative stress; berries and antioxidant
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

In recent years, an increasing number of studies have focused on the role of natural polyphenols—compounds found in plants such as fruits, vegetables, tea, and wine—in the prevention and management of chronic diseases, including cardiovascular diseases, cancer, neurodegenerative disorders, and type 2 diabetes. These compounds exhibit diverse health benefits through their antioxidant, anti-inflammatory, antimicrobial, and cardioprotective properties, counteracting oxidative stress and modulating cellular pathways linked to disease. While research suggests promising therapeutic roles, the specific mechanisms and optimal intake for human health remain investigation, and some compounds may have adverse effects when consumed in isolation.

This Special Issue will highlight recent advances in the field, with a focus on the cellular processes, molecular mechanisms, pathways modulated by these bioactive compounds, in order to promote their efficacy in diseases management. Both original research articles and review papers are welcome.

Prof. Dr. Massimiliano Gasparrini
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural polyphenols
  • dietary bioactive compounds
  • molecular mechanisms
  • health promotion
  • nutritional support

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