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Bioactive Natural Compounds in the Prevention and Treatment of Human and Veterinary Diseases

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 20 July 2026 | Viewed by 49

Special Issue Editors


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Guest Editor
Association for Research on Integrative Oncology Therapies (ARTOI), Via Ludovico Micara, 73, 00165 Rome, Italy
Interests: bioactive natural compounds; natural products; probiotics; prebiotics; drug resistance; inflammation; microbiology; virus-host cell interaction; virulence factors; viral receptors; viral entry; antiviral drugs; lactoferrin; lipophilic amines; antiviral peptides; natural and synthetic antiviral compounds
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Biochemical Sciences “Alessandro Rossi Fanelli”, “Sapienza” University of Rome, Piazzale Aldo Moro, 5, 00185 Rome, Italy
Interests: bioactive natural compounds; herbal products; inflammatory processes; intracellular pathways; extracellular matrix components; N-acetyl-glucosamine; acetyl-carnitine; nanomaterials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Bioactive natural compounds, endowed with properties such as antioxidant, anti-inflammatory, immunomodulatory, and antimicrobial activities, represent a promising preventive and therapeutic strategy against several pathological processes. They are widely used to treat or prevent a broad spectrum of conditions in both humans and animals. Furthermore, due to the side effects associated with conventional drugs and the growing problem of drug resistance, there is increasing interest in research on natural products and their possible synergistic effects. Since these compounds constitute a rich source of new therapeutics, research in this field continues to play an important role in identifying novel agents and uncovering new applications for known compounds.

This Special Issue aims to collect articles highlighting the importance of products of natural origin and to serve as a communication platform for researchers working in the field of bioactive natural compounds. Potential topics include, but are not limited to, the following: natural compounds; drug resistance; health promotion; disease prevention; disease treatment; synergistic effect; and mechanisms of action.

We welcome original research articles—whether in vitro, preclinical, or clinical—and review papers on the biological activities of natural products in both communicable and non-communicable diseases.

We look forward to receiving your contributions.

Dr. Fabiana Superti
Dr. Anna Scotto D'Abusco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive natural substances
  • nutraceuticals
  • drug discovery
  • drug resistance
  • inflammation
  • antioxidant
  • health promotion
  • prevention
  • treatment
  • synergistic effect
  • molecular mechanism
  • computational analysis
  • repurposed molecules

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Published Papers

This special issue is now open for submission.
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