Hyperglycemia Diagnosed in Pregnancy: Diagnosis, Interventions, Outcomes and Knowledge Gaps
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Women's Health".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 2347
Special Issue Editor
Interests: early origins of health and disease; non-communicable disorders in women; maternal health; diabetes; metabolism; obesity; gestational diabetes; insulin resistance; PCOS; endocrine disorders; menopause
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Special Issue Information
Dear Colleagues,
Hyperglycemia is among the most frequent yet serious complications of pregnancy. Although this disorder is commonly recognised as a major risk factor for fetomaternal adverse outcomes, such as excessive fetal growth, macrosomia, excessive maternal gestational weight gain, or hypertensive disorders of pregnancy, the magnitude of these interactions differs across the populations, and their mechanisms are yet to be fully elucidated.
Moreover, new areas of clinical and research interest are emerging, such as specific approaches to target populations at high risk for developing hyperglycemia in pregnancy and to detect hyperglycemia in early pregnancy, which leaves an open question of the usability of various criteria in early pregnancy or trimester-specific glycemic thresholds necessary for ameliorating fetomaternal risks. We are also gathering more evidence on nonglycemic risk factors for complications, including maternal gestational weight gain, environmental or lifestyle stressors, or alterations in maternal and placental metabolism, which can still only be partly tracked with increasing numbers of circulating biomarkers. There is also an increasing amount of evidence on an association between hyperglycemia in pregnancy and a vicious circle of premature morbidity for non-communicable disorders in mothers and their offspring. This recent evidence raises further questions about whether effective treatment of hyperglycemia in pregnancy could be translated into long-term benefits for both generations.
Therefore, we would like to invite experts in the field to share their results from observational and interventional clinical trials or mechanistic studies. We also expect reviews and meta-analyses identifying knowledge gaps in this area.
Dr. Agnieszka Zawiejska
Guest Editor
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Keywords
- gestational diabetes mellitus
- diabetes diagnosed in pregnancy
- hyperglycemia detected in early pregnancy
- maternal and fetal outcomes
- glycemic thresholds in pregnancy
- treatment of hyperglycemia in pregnancy
- maternal comorbidities in GDM pregnancy
- biomarkers of insulin resistance in GDM pregnancy
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