Biological Control of Integrated Pest Management in Horticulture Crops

A special issue of Horticulturae (ISSN 2311-7524). This special issue belongs to the section "Insect Pest Management".

Deadline for manuscript submissions: 15 October 2026 | Viewed by 2279

Special Issue Editors


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Guest Editor
College of Plant Protection, Henan Agricultural University, Zhengzhou 450002, China
Interests: pest management; biological control; RNAi; biological invasion; entomopathogenic fungi; endosymbiont

E-Mail Website
Guest Editor
Laboratorio di Entomologia ed Ecologia Applicata, Dipartimento PAU, Università Mediterranea di Reggio Calabria, 89124 Reggio Calabria, Italy
Interests: insect ecology; pest management; forest entomology; biological control; tritrophic interactions
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Special Issue Information

Dear Colleagues,

This Special Issue will focus on how biological control serves as the cornerstone of integrated pest management (IPM) in horticultural crops, providing effective, residue-safe, and climate-resilient alternatives to reliance on synthetic pesticides. We invite contributions that elucidate the ecology, mechanisms, implementation, and upscaling of biocontrol-based IPM strategies in fruit, vegetable, ornamental, nursery, and protected-culture systems under open-field or greenhouse conditions. We particularly welcome interdisciplinary studies that link fundamental research with practical IPM decision-making, farmer adoption, and policy or regulatory frameworks at regional and global scales. Topics of interest include, but are not limited to:

  • Ecology and mechanisms of biological control in horticultural systems;
  • Biocontrol agents and products for IPM in horticultural crops, including classical, augmentative, and conservation biocontrol;
  • IPM design, decision-support tools, and integration strategies at field, farm, and landscape scales;
  • Conservation and habitat management approaches that enhance functional biodiversity and natural enemy services;
  • Compatibility, risk assessment, and non-target effects of biocontrol agents and reduced-risk pesticides;
  • Emerging technologies empowering biocontrol-based IPM in horticulture, such as omics, microbiome engineering, remote sensing, precision agriculture, and digital decision tools, as well as case studies demonstrating successful implementation and impact assessment of biocontrol-based IPM programmes.

Dr. Chenchen Zhao
Dr. Carmelo Peter Bonsignore
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Horticulturae is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biological control
  • integrated pest management (IPM)
  • horticultural crops
  • predators and parasitoids
  • entomopathogenic fungi
  • entomopathogenic nematodes
  • microbial biocontrol agents
  • botanicals
  • semiochemicals and pheromones
  • conservation biological control

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Published Papers (1 paper)

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Review

19 pages, 321 KB  
Review
Spray-Applied RNA Interference Biopesticides: Mechanisms, Technological Advances, and Challenges Toward Sustainable Pest Management
by Xiang Li, Hang Lu, Chenchen Zhao and Qingbo Tang
Horticulturae 2026, 12(2), 137; https://doi.org/10.3390/horticulturae12020137 - 26 Jan 2026
Cited by 2 | Viewed by 1982
Abstract
Spray-induced gene silencing (SIGS) represents a transformative paradigm in sustainable pest management, utilizing the exogenous application of double-stranded RNA (dsRNA) to achieve sequence-specific silencing of essential genes in arthropod pests. Unlike transgenic approaches, sprayable RNA interference (RNAi) biopesticides offer superior versatility across crop [...] Read more.
Spray-induced gene silencing (SIGS) represents a transformative paradigm in sustainable pest management, utilizing the exogenous application of double-stranded RNA (dsRNA) to achieve sequence-specific silencing of essential genes in arthropod pests. Unlike transgenic approaches, sprayable RNA interference (RNAi) biopesticides offer superior versatility across crop systems, flexible application timing, and a more favorable regulatory and public acceptance profile. The 2023 U.S. EPA registration of Ledprona, the first sprayable dsRNA biopesticide targeting Leptinotarsa decemlineata, marks a significant milestone toward the commercialization of non-transformative RNAi technologies. Despite the milestone, large-scale field deployment faces critical bottlenecks, primarily environmental instability, enzymatic degradation by nucleases, and variable cellular uptake across pest taxa. This review critically analyzes the mechanistic basis of spray-applied RNAi and synthesizes the recent technological breakthroughs designed to overcome physiological and environmental barriers. We highlight advanced delivery strategies, including nuclease inhibitor co-application, liposome encapsulation, and nanomaterial-based formulations that enhance persistence on plant foliage and uptake efficiency. Furthermore, we discuss how innovations in microbial fermentation have drastically reduced synthesis costs, rendering industrial-scale production economically viable. Finally, we outline the roadmap for broad adoption, addressing essential factors such as biosafety assessment, environmental fate, resistance management protocols, and the path toward cost-effective manufacturing. Full article
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