Advanced Treatment and Care Management in Dementia: From Bench to Bedside

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 30 June 2024 | Viewed by 8434

Special Issue Editor


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Guest Editor
1. Institute of Clinical Medical Science, China Medical University, Taichung 404333, Taiwan
2. Department of Psychiatry & Brain Disease Research Center, China Medical University Hospital, Taichung 404332, Taiwan
3. An Nan Hospital, China Medical University, Tainan 709204, Taiwan
Interests: antipsychotics; schizophrenia; treatment

Special Issue Information

Dear Colleagues,

Dementia impairs multiple cognitive functions especially memory. It is a progressive neuropsychiatric disorder and affects daily function. Nowadays, Alzheimer disease (AD) is the leading cause of dementia among older populations, and the prevalence of AD-induced dementia is high at up to 4.02% among adults aged >60 years. Approximately 35.6 million adults worldwide developed dementia in 2010, and this number is projected to increase to 65.7 million in 2030. Worldwide spending on AD was approximately US$422 billion in 2009. The main pharmacologic treatments for AD patients are cholinesterase inhibitors and the N-methyl-D-aspartate receptor partial antagonist memantine. However, the treatment response is not satisfied and may cause adverse effects. Moreover, dementia not only impairs cognitive functions and quality of life in patients but also results in a heavy burden on caregivers, especially their families. Therefore, advanced treatment and care must be urgently developed for dementia.

Dr. Chun-Hung Chang
Guest Editor

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Keywords

  • dementia
  • Alzheimer disease
  • treatment
  • care

Published Papers (3 papers)

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Research

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10 pages, 825 KiB  
Article
A Survey of Mobile Apps for the Care Management of Patients with Dementia
by Hsiao-Lun Kuo, Chun-Hung Chang and Wei-Fen Ma
Healthcare 2022, 10(7), 1173; https://doi.org/10.3390/healthcare10071173 - 23 Jun 2022
Cited by 5 | Viewed by 2144
Abstract
Objective: Dementia is a progressive neurocognitive disorder that currently affects approximately 50 million people globally and causes a heavy burden for their families and societies. This study analyzed mobile apps for dementia care in different languages and during the COVID-19 pandemic. Methods: We [...] Read more.
Objective: Dementia is a progressive neurocognitive disorder that currently affects approximately 50 million people globally and causes a heavy burden for their families and societies. This study analyzed mobile apps for dementia care in different languages and during the COVID-19 pandemic. Methods: We searched PubMed, Cochrane Collaboration Central Register of Con-trolled Clinical Trials, Cochrane Systematic Reviews, Google Play Store, Apple App Store, and Huawei App Store for mobile applications for dementia care. The Mobile Application Rating Scale (MARS) was used to assess the quality of applications. Results: We included 99 apps for dementia care. No significant difference in MARS scores was noted between the two language apps (Overall MARS: English: 3.576 ± 0.580, Chinese: 3.569 ± 0.746, p = 0.962). In the subscale analysis, English apps had higher scores of perceived impact than Chinese apps but these were not significant (2.654 ± 1.372 vs. 2.000 ± 1.057, p = 0.061). (2) Applications during the COVID-19 pandemic had higher MARS scores than those before the COVID-19 pandemic but these were not significant (during the COVID-19 pandemic: 3.722 ± 0.416; before: 3.699 ± 0.615, p = 0.299). In the sub-scale analysis, apps during the COVID-19 pandemic had higher scores of engagement than apps before the COVID-19 pandemic but these were not significant (3.117 ± 0.594 vs. 2.698 ± 0.716, p = 0.068). Conclusions: Our results revealed that there is a minor but nonsignificant difference between different languages and during the COVID-19 pandemic. Further cooperation among dementia professionals, technology experts, and caregivers is warranted to provide evidence-based and user-friendly information to meet the needs of users. Full article
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18 pages, 320 KiB  
Article
Primary and Secondary Caregivers of People with Dementia (PwD): Differential Patterns and Implications for Psychological Support
by Arantxa Gorostiaga, Igone Etxeberria, Karmele Salaberria and Iñigo Kortabitarte
Healthcare 2022, 10(6), 1102; https://doi.org/10.3390/healthcare10061102 - 14 Jun 2022
Cited by 4 | Viewed by 1937
Abstract
Very little attention has been paid to identifying the differential characteristics of primary and secondary dementia caregivers. The aims of this study were: to determine whether differences exist between primary and secondary caregivers of people with dementia (PwD) and to explore the profile [...] Read more.
Very little attention has been paid to identifying the differential characteristics of primary and secondary dementia caregivers. The aims of this study were: to determine whether differences exist between primary and secondary caregivers of people with dementia (PwD) and to explore the profile of primary and secondary caregivers reporting symptoms of anxiety and/or depression. The participants were 146 caregivers of PwD, 73 primary caregivers and 73 secondary caregivers. The results revealed different patterns for each type of caregiver. Primary caregivers showed a more negative profile in terms of poorer self-rated health and higher levels of anxiety and depression: 61.6% of primary and 42.5% of secondary caregivers reported symptoms of anxiety, and 24.7% and 11% reported depression, respectively. The frequency of problem behavior, subjective burden, health, and the comorbidity between anxiety and depression were associated with depression and anxiety among primary caregivers, whereas gender (being a woman), subjective burden, health, and the comorbidity between anxiety and depression were associated among secondary caregivers. These findings may help to guide professionals in targeting psychological support programs and customizing the strategies and skills that need to be provided in accordance with the type of caregiver in question: primary or secondary. The practical implications of the findings are discussed. Full article

Review

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13 pages, 634 KiB  
Review
Occupational Therapy Interventions for Dementia Caregivers: Scoping Review
by Alberto Martínez-Campos, Laura-María Compañ-Gabucio, Laura Torres-Collado and Manuela Garcia-de la Hera
Healthcare 2022, 10(9), 1764; https://doi.org/10.3390/healthcare10091764 - 14 Sep 2022
Cited by 2 | Viewed by 3889
Abstract
Background and purpose: caregivers of people with dementia (PwD) often experience a significant caregiver burden. Occupational Therapy (OT) is a helpful discipline for improving quality of life and other health factors for these caregivers. We conducted a Scoping Review to describe OT interventions [...] Read more.
Background and purpose: caregivers of people with dementia (PwD) often experience a significant caregiver burden. Occupational Therapy (OT) is a helpful discipline for improving quality of life and other health factors for these caregivers. We conducted a Scoping Review to describe OT interventions for caregivers of PwD. Methods: two authors searched PubMed, Scopus, EMBASE and Web of Science databases and OT journals indexed in the Journal Citation Reports. Terms included in the search strategy were: dementia, Alzheimer, Parkinson, caregivers and OT. We included articles with experimental design in which an OT intervention in caregivers of PwD was carried out, written in Spanish or English and with the full text available. Results: a total of 2121 articles were obtained, 31 of which were included; 22 of them described home-based OT interventions: Tailored Activity Program (TAP) (n = 5), Environmental Skill-Building Program (ESP) (n = 4) and Advancing Caregiver Training (ACT) (n = 3) and other household interventions (n = 10); the remaining studies described OT interventions in other settings (n = 9). Conclusions: OT interventions for caregivers of PwD were mainly carried out at home. The most commonly used interventions were TAP focused on caregivers of people with Alzheimer’s disease, aimed at lessening the burden, depression and stress experienced by caregivers. Full article
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