Common Health Concerns in Older Women: Hormonal, Metabolic, Psychological, and Lifestyle Interactions

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Women’s and Children’s Health".

Deadline for manuscript submissions: 5 November 2026 | Viewed by 843

Special Issue Editor


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Guest Editor
Department of Applied Sciences to Work, University of Guanajuato, León Campus, Leon C.P. 37128, Mexico
Interests: women’s health; menopause; postmenopausal health; metabolic syndrome; obesity; cardiovascular risk; physical activity; stress and mental health; preventive medicine; integrative healthcare

Special Issue Information

Dear Colleagues,

In modern society, across the world, middle-aged and older women are experiencing major lifestyle and hormonal changes that interact with increasing psychosocial stressors (including media overload, social isolation, and the emotional demands of rapidly changing environments). These factors can affect neuroendocrine balance, which in turn contributes to sleep disturbances, psychological stress, and metabolic dysregulation. During menopausal transition and aging, hormonal and metabolic alterations converge with these neurophysiological and behavioral changes, heightening the risk of overweight, obesity, metabolic syndrome, cardiovascular disease, anxiety, and depression. Understanding these interrelated clinical and behavioral processes is crucial in improving prevention, diagnosis, and treatment strategies to promote health and quality of life in older women.

This Special Issue will explore the hormonal, metabolic, psychological, and lifestyle determinants that influence health and disease in midlife and older women. In line with the multidisciplinary scope of Healthcare, we welcome studies integrating clinical, physiological, psychosocial, and behavioral perspectives to advance our understanding of the complex mind–body interactions underlying women’s health during the climacteric and postmenopausal stages. We particularly encourage submissions employing innovative and integrative approaches (for example, assessments using heart rate variability, clinical screening tools, physical performance tests, or health monitoring systems).

Suggested Themes and Article Types

For this Special Issue, original research articles, systematic reviews, and meta-analyses are welcome. Research areas may include, but are not limited to, stress, hormonal, metabolic, and lifestyle determinants of women health and disease during menopause and aging and obesity, metabolic syndrome, and cardiovascular risk in older women, as well as physical activity, exercise, and rehabilitation programs. Studies addressing nutrition, sleep, and circadian health are also encouraged, along with research taking a mind–body approach (for example, mindfulness and meditation) to explore relevant health outcomes, including stress perception, cardiovascular metabolic health, mental health status, and translational, community-based, or lifestyle interventions that promote healthy aging.

We look forward to receiving your contributions to this Special Issue.

Dr. María Raquel Huerta-Franco
Guest Editor

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Keywords

  • midlife women
  • aging
  • hormonal regulation
  • metabolic health
  • cardiovascular risk
  • psychological well-being
  • lifestyle interventions
  • mind–body medicine
  • exercise and nutrition
  • integrative healthcare

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Published Papers (1 paper)

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Research

14 pages, 409 KB  
Article
Ultra-Processed Food Consumption and Domain-Specific Quality of Life in Postmenopausal Women: Associations with Mobility and Mental Health
by Byung Soo Kwan, Jung-Hwan Cho, Jun Young Kim, Hye In Kim, Nak Gyeong Ko and Ji Eun Park
Healthcare 2026, 14(6), 791; https://doi.org/10.3390/healthcare14060791 - 20 Mar 2026
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Abstract
Background/Objectives: Ultra-processed food (UPF) consumption is increasing worldwide, yet its domain-specific impact on health-related quality of life (HRQoL) among postmenopausal women remains poorly characterized. This study investigated associations between UPF intake and domain-specific and overall HRQoL in a nationally representative sample of Korean [...] Read more.
Background/Objectives: Ultra-processed food (UPF) consumption is increasing worldwide, yet its domain-specific impact on health-related quality of life (HRQoL) among postmenopausal women remains poorly characterized. This study investigated associations between UPF intake and domain-specific and overall HRQoL in a nationally representative sample of Korean postmenopausal women. Methods: Data from the Korea National Health and Nutrition Examination Survey (2013–2021) were analyzed. UPF consumption was assessed using a single 24 h dietary recall and classified according to the NOVA food classification system. HRQoL was evaluated using the five EQ-5D domains and the overall EQ-5D index. Survey-weighted logistic regression models estimated odds ratios (ORs) and 95% confidence intervals (CIs) across UPF intake quartiles, adjusting for socioeconomic and health-related covariates. Results: Higher UPF consumption was associated with impairments in specific HRQoL domains rather than a uniform decline across domains. In fully adjusted models, women in the third UPF intake quartile had higher odds of mobility impairment (OR 1.74; 95% CI 1.06–2.86) and anxiety/depression symptoms (OR 1.71; 95% CI 1.06–2.77) than those in the lowest quartile. A significant linear trend was observed for mobility (P-for-trend = 0.012). In contrast, associations with the overall EQ-5D index score were limited and not consistently observed after full adjustment. Conclusions: Higher UPF consumption is associated with domain-specific HRQoL impairments, particularly affecting physical mobility and mental health, among postmenopausal women. These findings underscore the importance of domain-specific assessments and suggest that UPF consumption may be related to certain aspects of functional and psychological well-being after menopause. Full article
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