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New Advances in Joint Osteoarthritis
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New Advances in Joint Osteoarthritis

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Chronic Care".

Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 6417

Special Issue Editors

Dr. Eugenio Jannelli

E-Mail Website
Guest Editor
Multidisciplinary Department of Medico-Surgical and Dentistry Specialties, Luigi Vanvitelli, University of Campania, 80138 Naples, Italy
Interests: knee; hip; TKA; THA; traumatology; regenerative medicine; biological therapy
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Federico Grassi

E-Mail Website
Guest Editor
Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy
Interests: shoulder; knee; hip; THA; TKA; RSA

Special Issue Information

Dear Colleagues,

Osteoarthritis (OA) is the most common joint disease, and estimates suggest that it affects more than 240 million people worldwide, including more than 32 million in the US. Osteoarthritis is the most frequent reason for activity limitation in adults. Therapeutic approaches have predominantly addressed symptoms and tried to modify/improve the structural features of affected joint tissues. The development of novel therapeutic approaches targeting the osteoarthritic degradative and inflammatory processes in cartilage, synovium, or bone requires a deep understanding of the disease status of these joint tissues at the time of intervention. With the growth of surgical skills in the context of hip and knee arthroscopy, cartilage restoration techniques are evolving in a fast and exponential manner. Biological and surgical treatments have been proposed to treat these pathologies (the biological treatments include the use of platelet-rich plasma, stem cells, or bone marrow aspirate concentrations, hyaluronic acid, and others. However, for many people, joint replacement surgery has been the only option available to repair joints damaged by osteoarthritis. The developments in hip and knee arthroplasty over recent years have aimed to improve outcomes, reduce complications, and improve implant survival. Notable developments have included ceramic hip resurfacing, mini hip stems, cementless knee replacement, and the wider adoption of dual mobility articulation for hip arthroplasty. This Special Issue aims to showcase selected contributions on new advances in knee and hip Osteoarthritis. Potential research topics include (but are not limited to) the following:

  • The potential for new radiological classification systems for OA;
  • Cell-based therapies for low- and intermediate-grade OA;
  • Effectiveness of infiltrative therapy with different types of hyaluronic acid;
  • Osteoarthritis and sports;
  • New challenge in prosthetic design for the treatment of knee OA;
  • New challenge in prosthetic design for the treatment of hip OA;
  • Tribology in TKA and THA;
  • Experiences with Robotic-assisted surgery.

Dr. Eugenio Jannelli
Prof. Dr. Federico Grassi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • knee
  • hip
  • arthroplasty
  • regenerative medicine
  • TKA
  • THA
  • robotic assisted surgery

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Published Papers (3 papers)

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11 pages, 1974 KiB  
Article
Bilateral Total Knee Arthroplasty (TKA) in a One-Stage Procedure Versus Two-Stage Procedure: A Retrospective Study
by Giada Accatino, Alessandra Monzio Compagnoni, Federico Alberto Grassi, Alberto Castelli, Gianluigi Pasta, Francesco Benazzo, Stefano Marco Paolo Rossi and Eugenio Jannelli
Healthcare 2024, 12(18), 1902; https://doi.org/10.3390/healthcare12181902 - 23 Sep 2024
Cited by 2 | Viewed by 1502
Abstract
Background/Objectives: This retrospective study aims to evaluate the safety and functional outcomes of simultaneous bilateral total knee arthroplasty (TKA) compared to two-stage bilateral TKA procedures. Osteoarthritis is the leading cause of knee joint replacement globally, so we sought to determine whether the one-stage [...] Read more.
Background/Objectives: This retrospective study aims to evaluate the safety and functional outcomes of simultaneous bilateral total knee arthroplasty (TKA) compared to two-stage bilateral TKA procedures. Osteoarthritis is the leading cause of knee joint replacement globally, so we sought to determine whether the one-stage approach could be deemed non-inferior to the two-stage method in terms of perioperative complications and postoperative recovery. Methods: We analyzed two cohorts: 43 patients underwent one-stage bilateral TKA, while 66 patients received two-stage TKA. The data collected included demographic details, comorbidities, postoperative complications, and functional outcomes assessed by the Oxford Knee Score (OKS), European Quality of Life, and Visual Analogue Scale scores at preoperative and five years postoperative follow-ups. Results: The results showed statistically significant improvements in quality-of-life measures for both groups, with the one-stage group exhibiting greater enhancement in OKS (p < 0.05). Complication rates were similar across both procedures, with no significant differences in infection rates or other adverse events. Conclusions: This study suggests that the one-stage approach to treat bilateral knee arthritis could reduce subjective stress and healthcare costs, presenting a safe alternative for appropriately selected patients. However, the findings highlight the necessity of considering patients’ overall health status when planning surgical interventions. Further research involving larger populations is recommended to validate our conclusions. Full article
(This article belongs to the Special Issue New Advances in Joint Osteoarthritis)
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14 pages, 2645 KiB  
Article
Problems and Opportunities of a Smartphone-Based Care Management Platform: Application of the Wald Principles to a Survey-Based Analysis of Patients’ Perception in a Pilot Center
by Stefano Marco Paolo Rossi, Rocco Maria Panzera, Rudy Sangaletti, Luca Andriollo, Laura Giudice, Francesca Lecci and Francesco Benazzo
Healthcare 2024, 12(2), 153; https://doi.org/10.3390/healthcare12020153 - 9 Jan 2024
Cited by 20 | Viewed by 1984
Abstract
(1) Background: Mobile health (mHealth) solutions can become a means of improving functional recovery and reducing the peri-operative burden and costs associated with arthroplasty procedures. The aim of this study is to explore the objectives, functionalities, and outcomes of a platform designed to [...] Read more.
(1) Background: Mobile health (mHealth) solutions can become a means of improving functional recovery and reducing the peri-operative burden and costs associated with arthroplasty procedures. The aim of this study is to explore the objectives, functionalities, and outcomes of a platform designed to provide personalized surgical experiences to qualified patients, along with the associated problems and opportunities. (2) Methods: A survey-based analysis was conducted on patients who were prescribed the use of a specific care management platform and underwent primary robotic total knee arthroplasty (rTKA) between January 2021 and February 2023. (3) Results: Patients registered on the platform who have undergone primary robotic TKA (rTKA) were considered. The mean age of registered patients is 68.6 years. The male (M)/female (F) ratio is 45.1%/54.9%. The patients interviewed were at an average distance of 485 days from the intervention, with a standard deviation of 187.5. The survey highlighted appreciation for the app and its features, but also limitations in its use and in its perception by the patients. All these data were evaluated according to the Wald principles and strategies to improve patient recruitment, enhance adherence, and create a comprehensive patient journey for optimized surgical experiences. (4) Conclusions: This patient care platform may have the potential to impact surgical experiences by increasing patient engagement, facilitating remote monitoring, and providing personalized care. There is a need to emphasize the importance of integrating the recruiting process, improving adherence strategies, and creating a comprehensive patient journey within the platform. Full article
(This article belongs to the Special Issue New Advances in Joint Osteoarthritis)
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10 pages, 15426 KiB  
Case Report
One-Stage Tricompartmental Hypoallergenic UKA for Tricompartmental Osteoarthritis: A Case Report
by Andrea Parente, Marta Medetti, Giuseppe Basile and Franco Parente
Healthcare 2023, 11(22), 2999; https://doi.org/10.3390/healthcare11222999 - 20 Nov 2023
Cited by 1 | Viewed by 2368
Abstract
Osteoarthritis (OA) is a degenerative and progressive joint disease. When all three compartments are involved, end-stage OA is treated with a total knee arthroplasty (TKA). Unicompartmental knee arthroplasty (UKA) is a primary treatment for isolated osteoarthritis. UKA has a quicker recovery time than [...] Read more.
Osteoarthritis (OA) is a degenerative and progressive joint disease. When all three compartments are involved, end-stage OA is treated with a total knee arthroplasty (TKA). Unicompartmental knee arthroplasty (UKA) is a primary treatment for isolated osteoarthritis. UKA has a quicker recovery time than TKA, as well as less morbidity and more tissue sparing. At the time of surgery, 17% of patients have a tricompartmental disease and most patients with a Kellegren–Lawrence grade >3 have an intact anterior cruciate ligament (ACL). Conventional TKA sacrifices the ACL. Patients with concurrent medial and lateral osteoarthritis and a functional ACL may receive a primary bi-unicondylar arthroplasty. Combined partial knee arthroplasty (CPKA) is an established practice either in bicompartmental femoro-tibial OA or in OA progression after UKA, with the addition of another UKA. A conversion of a lateral UKA to a tricompartmental joint replacement has been reported in the literature. In our case report, we describe a one-stage hypoallergenic tricompartmental UKA, with improved clinical score and no sign of early failure at the last follow-up. Full article
(This article belongs to the Special Issue New Advances in Joint Osteoarthritis)
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