Cardiovascular Health and Stroke

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: closed (30 December 2023) | Viewed by 5712

Special Issue Editors


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Guest Editor
Department of Pulmonary and Critical Care Medicine, Jacksonville, FL 32224, USA
Interests: heart failure and shock; ARDS; myocardial infarction; personalized medicine; artifical intelligence in healthcare

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Guest Editor
Department of Internal Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Interests: COVID 19 and cardiovascular outcomes; valvular heart diseases; epidemiology and population based studies
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Special Issue Information

Dear Colleagues,

We are pleased to invite you to submit your research to this Special Issue of Healthcare on “Cardiovascular Health and Stroke”. Research advancements in the field of cardiovascular health and stroke have been rapidly progressing, especially in the areas of precision medicine, identifying novel pathogenesis and therapeutic targets, identifying disparities in healthcare, and improving outcomes with bioinformatics and artificial intelligence.

This Special Issue aims to publish original studies, including both clinical trials and observational studies, and reviews (systematic and/or meta-analyses) that focus on:

  • Recent advances in the diagnosis and management of cardiovascular diseases and stroke, including the use of artificial intelligence, precision medicine and bio-innovation;
  • Gender, ethnical and racial disparities, as well as other recent health challenges including COVID-19, in the diagnosis, treatment and outcomes of cardiovascular diseases and stroke.

We look forward to receiving your contributions.

Dr. Prasanth Balasubramanian
Dr. Adrija Hajra
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular health and stroke
  • precision medicine
  • artificial intelligence
  • bio-innovation
  • disparities
  • outcomes
  • challenges

Published Papers (3 papers)

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Research

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13 pages, 578 KiB  
Article
The Cost and the Value of Stroke Care in Greece: Results from the SUN4P Study
by Olga Siskou, Petros Galanis, Olympia Konstantakopoulou, Panagiotis Stafylas, Iliana Karagkouni, Evangelos Tsampalas, Dafni Garefou, Helen Alexopoulou, Anastasia Gamvroula, Maria Lypiridou, Ioannis Kalliontzakis, Anastasia Fragkoulaki, Aspasia Kouridaki, Argyro Tountopoulou, Ioanna Kouzi, Sofia Vassilopoulou, Efstathios Manios, Georgios Mavraganis, Anastasia Vemmou, Efstathia Karagkiozi, Christos Savopoulos, Gregorios Dimas, Athina Myrou, Haralampos Milionis, Georgios Siopis, Hara Evaggelou, Athanasios Protogerou, Stamatina Samara, Asteria Karapiperi, Nikolaos Kakaletsis, George Papastefanatos, Stefanos Papastefanatos, Panayota Sourtzi, George Ntaios, Konstantinos Vemmos, Eleni Korompoki and Daphne Kaitelidouadd Show full author list remove Hide full author list
Healthcare 2023, 11(18), 2545; https://doi.org/10.3390/healthcare11182545 - 14 Sep 2023
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Abstract
The aim of this study was to measure the one-year total cost of strokes and to investigate the value of stroke care, defined as cost per QALY. The study population included 892 patients with first-ever acute strokes, hemorrhagic strokes, and ischemic strokes, (ICD-10 [...] Read more.
The aim of this study was to measure the one-year total cost of strokes and to investigate the value of stroke care, defined as cost per QALY. The study population included 892 patients with first-ever acute strokes, hemorrhagic strokes, and ischemic strokes, (ICD-10 codes: I61, I63, and I64) admitted within 48 h of symptoms onset to nine public hospitals located in six cities. We conducted a bottom-up cost analysis from the societal point of view. All cost components including direct medical costs, productivity losses due to morbidity and mortality, and informal care costs were considered. We used an annual time horizon, including all costs for 2021, irrespective of the time of disease onset. The average cost (direct and indirect) was extrapolated in order to estimate the national annual burden associated with stroke. We estimated the total cost of stroke in Greece at EUR 343.1 mil. a year in 2021, (EUR 10,722/patient or EUR 23,308 per QALY). Out of EUR 343.1 mil., 53.3% (EUR 182.9 mil.) consisted of direct healthcare costs, representing 1.1% of current health expenditure in 2021. Overall, productivity losses were calculated at EUR 160.2 mil. The mean productivity losses were estimated to be 116 work days with 55.1 days lost due to premature retirement and absenteeism from work, 18.5 days lost due to mortality, and 42.4 days lost due to informal caregiving by family members. This study highlights the burden of stroke and underlines the need for stakeholders and policymakers to re-organize stroke care and promote interventions that have been proven cost-effective. Full article
(This article belongs to the Special Issue Cardiovascular Health and Stroke)
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Review

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10 pages, 242 KiB  
Review
The Role of ChatGPT in the Advancement of Diagnosis, Management, and Prognosis of Cardiovascular and Cerebrovascular Disease
by David-Dimitris Chlorogiannis, Anastasios Apostolos, Anargyros Chlorogiannis, Leonidas Palaiodimos, George Giannakoulas, Sumant Pargaonkar, Sofia Xesfingi and Damianos G. Kokkinidis
Healthcare 2023, 11(21), 2906; https://doi.org/10.3390/healthcare11212906 - 6 Nov 2023
Cited by 1 | Viewed by 2094
Abstract
Cardiovascular and cerebrovascular disease incidence has risen mainly due to poor control of preventable risk factors and still constitutes a significant financial and health burden worldwide. ChatGPT is an artificial intelligence language-based model developed by OpenAI. Due to the model’s unique cognitive capabilities [...] Read more.
Cardiovascular and cerebrovascular disease incidence has risen mainly due to poor control of preventable risk factors and still constitutes a significant financial and health burden worldwide. ChatGPT is an artificial intelligence language-based model developed by OpenAI. Due to the model’s unique cognitive capabilities beyond data processing and the production of high-quality text, there has been a surge of research interest concerning its role in the scientific community and contemporary clinical practice. To fully exploit ChatGPT’s potential benefits and reduce its possible misuse, extreme caution must be taken to ensure its implications ethically and equitably. In this narrative review, we explore the language model’s possible applications and limitations while emphasizing its potential value for diagnosing, managing, and prognosis of cardiovascular and cerebrovascular disease. Full article
(This article belongs to the Special Issue Cardiovascular Health and Stroke)

Other

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18 pages, 2214 KiB  
Systematic Review
Right-to-Left Shunt in Divers with Neurological Decompression Sickness: A Systematic Review and Meta-Analysis
by Spyros Peppas, Leonidas Palaiodimos, Sanjana Nagraj, Damianos G. Kokkinidis, Nidhish Tiwari, Amrin Kharawala, Mohammad K. Mojadidi, Sanauallah Mojaddedi, George Ntaios, Robert T. Faillace and Jonathan M. Tobis
Healthcare 2023, 11(10), 1407; https://doi.org/10.3390/healthcare11101407 - 12 May 2023
Cited by 1 | Viewed by 1207
Abstract
Objective: The aim of this study was to assess the association between the presence of a right-to-left shunt (RLS) and neurological decompression sickness (NDCS) and asymptomatic brain lesions among otherwise healthy divers. Background: Next to drowning, NDCS is the most severe phenotype of [...] Read more.
Objective: The aim of this study was to assess the association between the presence of a right-to-left shunt (RLS) and neurological decompression sickness (NDCS) and asymptomatic brain lesions among otherwise healthy divers. Background: Next to drowning, NDCS is the most severe phenotype of diving-related disease and may cause permanent damage to the brain and spinal cord. Several observational reports have described the presence of an RLS as a significant risk factor for neurological complications in divers, ranging from asymptomatic brain lesions to NDCS. Methods: We systematically reviewed the MEDLINE, Embase, and CENTRAL databases from inception until November 2021. A random-effects model was used to compute odds ratios. Results: Nine observational studies consisting of 1830 divers (neurological DCS: 954; healthy divers: 876) were included. RLS was significantly more prevalent in divers with NDCS compared to those without (62.6% vs. 27.3%; odds ratio (OR): 3.83; 95% CI: 2.79–5.27). Regarding RLS size, high-grade RLS was more prevalent in the NDCS group than the no NDCS group (57.8% versus 18.4%; OR: 4.98; 95% CI: 2.86–8.67). Further subgroup analysis revealed a stronger association with the inner ear (OR: 12.13; 95% CI: 8.10–18.17) compared to cerebral (OR: 4.96; 95% CI: 2.43–10.12) and spinal cord (OR: 2.47; 95% CI: 2.74–7.42) DCS. RLS was more prevalent in divers with asymptomatic ischemic brain lesions than those without any lesions (46.0% vs. 38.0%); however, this was not statistically significant (OR: 1.53; 95% CI: 0.80–2.91). Conclusions: RLS, particularly high-grade RLS, is associated with greater risk of NDCS. No statistically significant association between RLS and asymptomatic brain lesions was found. Full article
(This article belongs to the Special Issue Cardiovascular Health and Stroke)
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