Advanced Gel-Based Materials and Coatings with Enhanced Bioactivity

A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Applications".

Deadline for manuscript submissions: 20 October 2024 | Viewed by 835

Special Issue Editors


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Guest Editor
FibEnTech Research Unit, Faculty of Engineering, University of Beira Interior, 6200-001 Covilhã, Portugal
Interests: antimicrobial function; nanofiber structures; microplastic; gels; bacterial cellulose; sustainable; biomedical applications
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
FibEnTech Research Unit, Faculty of Engineering, University of Beira Interior, 6200-001 Covilhã, Portugal
Interests: electrospinning; biomaterials; gels; antibacterial

Special Issue Information

Dear Colleagues,

We cordially invite submissions for our Special Issue dedicated to exploring the vast domain of advanced gel-based materials and coatings, specifically those accentuating their heightened bioactivity directed towards mitigating biofilm formation in diverse sectors.

This Special Issue aims to consolidate research elucidating antimicrobial functionalities across a spectrum of applications encompassing medical and hospital contexts—such as medical devices, surface treatments, and air and water systems—as well as within the domains of the food industry, pharmaceutics, textiles, and various material surfaces. Our focal point is to curate insights and innovations advancing the efficacy of gel-based solutions in combatting biofilm formation across these multifaceted arenas.

The primary objective of this initiative is to spotlight innovative methodologies and advancements in the realm of gel-based materials and coatings. By harnessing biobased solutions and cutting-edge gel technologies, our endeavor can advance sustainable development amid the challenges posed by climate change, while steering away from conventional fossil-based materials. Concurrently, we aim to amalgamate biomimetic and bio-inspired strategies, fostering bioactive functionalities while addressing pertinent concerns surrounding bacterial resistance.

Topics of interest encompass, but are not confined to:

  • Novel bioactive materials showcasing amplified antimicrobial properties;
  • Development and characterization of antimicrobial surfaces and coatings;
  • Explorations in biobased solutions demonstrating efficacy against microbial growth;
  • Biomimetic approaches employed for advancing bioactive functionalities;
  • Integration of principles ensuring safe-by-design development of bioactive functionalities.

We welcome researchers, academics, and industry experts to submit abstracts elucidating groundbreaking research, novel methodologies, and significant breakthroughs in the realm of gel-based materials and coatings, with a dedicated focus on strengthening bioactivity against biofilm formation.

Dr. Isabel Gouveia
Dr. Cláudia Mouro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive function
  • antimicrobial coatings
  • antimicrobial materials
  • bioactive gels
  • biofilms
  • bacteria resistance

Published Papers (1 paper)

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Research

17 pages, 2672 KiB  
Article
Alginate- and Chitosan-Modified Gelatin Hydrogel Microbeads for Delivery of E. coli Phages
by Farzaneh Moghtader, Sencer Solakoglu and Erhan Piskin
Gels 2024, 10(4), 244; https://doi.org/10.3390/gels10040244 - 02 Apr 2024
Viewed by 621
Abstract
Bacterial infections are among the most significant health problems/concerns worldwide. A very critical concern is the rapidly increasing number of antibiotic-resistant bacteria, which requires much more effective countermeasures. As nature’s antibacterial entities, bacteriophages shortly (“phages”) are very important alternatives to antibiotics, having many [...] Read more.
Bacterial infections are among the most significant health problems/concerns worldwide. A very critical concern is the rapidly increasing number of antibiotic-resistant bacteria, which requires much more effective countermeasures. As nature’s antibacterial entities, bacteriophages shortly (“phages”) are very important alternatives to antibiotics, having many superior features compared with antibiotics. The development of phage-carrying controlled-release formulations is still challenging due to the need to protect their activities in preparation, storage, and use, as well as the need to create more user-friendly forms by considering their application area/site/conditions. Here, we prepared gelatin hydrogel microbeads by a two-step process. Sodium alginate was included for modification within the initial recipes, and these composite microbeads were further coated with chitosan. Their swelling ratio, average diameters, and Zeta potentials were determined, and degradations in HCl were demonstrated. The target bacteria Escherichia coli (E.coli) and its specific phage (T4) were obtained from bacterial culture collections and propagated. Phages were loaded within the microbeads with a simple method. The phage release characteristics were investigated comparatively and were demonstrated here. High release rates were observed from the gelatin microbeads. It was possible to reduce the phage release rate using sodium alginate in the recipe and chitosan coating. Using these gelatin-based microbeads as phage carrier matrices—especially in lyophilized forms—significantly improved the phage stability even at room temperature. It was concluded that phage release from gelatin hydrogel microbeads could be further controlled by alginate and chitosan modifications and that user-friendly lyophilized phage formulations with a much longer shelf life could be produced. Full article
(This article belongs to the Special Issue Advanced Gel-Based Materials and Coatings with Enhanced Bioactivity)
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