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Tracking Food Additives, Pesticide Residues, Food Contaminants, Novel Foods, and...
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Tracking Food Additives, Pesticide Residues, Food Contaminants, Novel Foods, and Food Allergens Using Footprint Analysis Based on Regulatory Requirements

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Analytical Methods".

Deadline for manuscript submissions: closed (30 June 2025) | Viewed by 1559

Special Issue Editor

Dr. Kosuke Nakamura

E-Mail Website
Guest Editor
Division of Foods, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki 210-9501, Kanagawa, Japan
Interests: food hygiene; food chemistry; food science; nutrients; pesticides; contaminants; novel foods; allergens; analytical methods; exposure assessment

Special Issue Information

Dear Colleagues,

Food hygiene is a cornerstone of public health, yet its management faces complex challenges due to diverse regulatory frameworks across the globe. Each nation employs distinct standards and inspection/analytical methods to ensure food safety, reflecting unique priorities, cultural practices, and regulatory environments. These differences can create significant hurdles for global trade, innovation, and the harmonization of safety protocols.

This Special Issue, “Tracking Food Additives, Pesticide Residues, Food Contaminants, Novel Foods, and Food Allergens Using Footprint Analysis Based on Regulatory Requirements”, seeks to explore groundbreaking strategies that address these challenges. We are particularly interested in research leveraging footprint analysis—a promising tool for tracking, assessing, and enhancing hygiene systems—and the application of regulatory science to align practices with global safety standards while respecting local regulations.

We invite submissions that propose innovative models, case studies, or frameworks aimed at improving hygiene monitoring, risk assessment, and regulatory compliance. By bridging gaps in scientific understanding and regulatory application, this Special Issue aspires to advance knowledge and foster collaboration in the pursuit of safer, more efficient food hygiene systems worldwide.

Join us in shaping the future of food safety by contributing your expertise to this timely and critical discourse.

Dr. Kosuke Nakamura
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food hygiene management
  • footprint analysis
  • regulatory science
  • global food safety standards
  • hygiene monitoring systems
  • risk assessment in food safety
  • inspection/analytical methods and innovation
  • harmonization of regulations
  • food safety and public health
  • sustainable hygiene practices

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Published Papers (2 papers)

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Research

14 pages, 1110 KB  
Article
Allergens in Food: Analytical LC-MS/MS Method for the Qualitative Detection of Pistacia vera
by Roberta Giugliano, Sara Morello, Samantha Lupi, Barbara Vivaldi, Daniela Manila Bianchi and Elisabetta Razzuoli
Foods 2025, 14(17), 3031; https://doi.org/10.3390/foods14173031 - 29 Aug 2025
Viewed by 705
Abstract
Pistachio (Pistacia vera) is widely consumed among tree nuts but capable of triggering severe IgE-mediated reactions in allergic individuals. Due to the similarity of cashew-borne and pistachio-borne allergen proteins and DNA, traditional detection methods, such as ELISA and PCR, often suffer [...] Read more.
Pistachio (Pistacia vera) is widely consumed among tree nuts but capable of triggering severe IgE-mediated reactions in allergic individuals. Due to the similarity of cashew-borne and pistachio-borne allergen proteins and DNA, traditional detection methods, such as ELISA and PCR, often suffer from cross-reactivity, limiting their ability to discriminate between these two allergens. This study presents a sensitive LC-MS/MS method for the simultaneous detection of pistachio and cashew allergens in processed food with a screening detection limit (SDL) equal to 1 mg/kg. The method was validated for specificity, SDL, β error, precision, and ruggedness, and applied to various matrices (cereals, chocolate, sauces, and meat products). Ruggedness testing showed that all considered parameters must be carefully monitored by the operator, and sample preparation must be carried out without any modification in parameter values, under strictly controlled conditions. Good reproducibility was achieved for pistachio detection, while ongoing investigations should be carried out to overcome existing constraints for cashew. The LC-MS/MS method described in this work is a discriminatory method suitable for official food allergen control to selectively differentiate pistachio from cashew allergens, overcoming the limitations of PCR and ELISA when cross-reactivity occurs. It represents a validated tool for pistachio detection and a promising approach toward improving cashew allergen analysis. Full article
(This article belongs to the Special Issue Tracking Food Additives, Pesticide Residues, Food Contaminants, Novel Foods, and Food Allergens Using Footprint Analysis Based on Regulatory Requirements)
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12 pages, 1539 KB  
Article
Evaluation of Chronic Dietary Risk of Trifloxystrobin and Bupirimate in Cucumber Based on Supervised Residue Test
by Yanli Qi, Weirong Wang, Pengcheng Ren, Shu Qin, Jindong Li and Junli Cao
Foods 2025, 14(10), 1745; https://doi.org/10.3390/foods14101745 - 14 May 2025
Viewed by 568
Abstract
Trifloxystrobin and bupirimate are widely used as fungicides for controlling powdery mildew in cucumber cultivation. Supervised field trials were conducted in 12 representative regions across China, following Good Agricultural Practices (GAP) guidelines, to investigate their residue patterns and potential dietary exposure risks. Cucumber [...] Read more.
Trifloxystrobin and bupirimate are widely used as fungicides for controlling powdery mildew in cucumber cultivation. Supervised field trials were conducted in 12 representative regions across China, following Good Agricultural Practices (GAP) guidelines, to investigate their residue patterns and potential dietary exposure risks. Cucumber samples were analyzed using a validated method involving extraction with acidified acetonitrile (2% acetic acid, v/v), cleanup with primary secondary amine (PSA) and graphitised carbon black (GCB), and quantification by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The method demonstrated excellent recovery rates (85–103%) throughout four spiking levels (0.01, 0.1, 0.3, and 1 mg/kg), with relative standard deviations (RSD) ≤ 4.8%. At 3 days after treatment, the residues of trifloxystrobin (including trifloxystrobin acid), bupirimate, and ethirimol in cucumbers were found to range from <0.01 to 0.013 mg/kg, <0.01 to 0.076 mg/kg, and <0.01 to 0.04 mg/kg, respectively. A chronic dietary risk assessment was conducted using a probabilistic model. The results showed an acceptable chronic risk (RQc ≤ 2.476%) for trifloxystrobin, bupirimate, and ethirimol across different sexes and ages, supporting the conclusion that the use of these fungicides in cucumber cultivation under the tested conditions was safe for Chinese consumers. More research was needed on children because they are at higher risk than other groups. Full article
(This article belongs to the Special Issue Tracking Food Additives, Pesticide Residues, Food Contaminants, Novel Foods, and Food Allergens Using Footprint Analysis Based on Regulatory Requirements)
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