The Effect of Food Bioactive Compounds on Reducing Oxidative Stress

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Nutraceuticals, Functional Foods, and Novel Foods".

Deadline for manuscript submissions: 1 July 2025 | Viewed by 739

Special Issue Editor


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Guest Editor
School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, China
Interests: natural food active ingredients; polyphenol phytochemicals; anti-dyslipidemia; aging and neuroprotection

Special Issue Information

Dear Colleagues,

Numerous studies have shown that food anti-oxidative stress is closely related to the prevention of chronic diseases (e.g., cardiovascular disease, diabetes, cancer, neurodegeneration etc.). Antioxidant ingredients are able to intervene in oxidative stress-mediated inflammatory responses, apoptosis, vascular endothelial dysfunction, and other pathological processes, thereby reducing the risk of chronic diseases. The antioxidant properties of phytochemicals such as polyphenols (e.g., flavonoids, phenolic acids), carotenoids, etc., can be explored in different foods. Their excellent efficacy can be further studied in terms of free radical scavenging, regulating the activity of antioxidant enzymes, and inhibiting lipid peroxidation. This Special Issue aims to bring together cutting-edge research results to explore the health benefits, mechanisms, and applications of food components, dietary patterns, and related factors in coping with oxidative stress in the body.

Prof. Dr. Jianmei Li
Guest Editor

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Keywords

  • food or food bioactive compounds
  • antioxidant active ingredients
  • phytochemicals
  • functional foods and dietary supplements
  • vitamins and minerals
  • natural foods
  • anti-aging
  • hepatoprotection
  • neuroprotection
  • anti-dyslipidemia
  • anti-inflammation

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Published Papers (1 paper)

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Review

18 pages, 1741 KiB  
Review
Nitraria sibirica Pall.: A Halophytic Resource for Antioxidant-Rich Functional Foods and Ecological Resilience
by Keyi Lu, Xinmei Zhang, Liping Zhao, Jikun Xu and Jianmei Li
Foods 2025, 14(9), 1646; https://doi.org/10.3390/foods14091646 - 7 May 2025
Viewed by 229
Abstract
Nitraria sibirica Pall., a halophytic shrub native to arid and saline–alkaline ecosystems, represents a dual-purpose resource for ecological stabilization and functional food development. This review synthesizes current knowledge of its bioactive compounds and pharmacological properties, while identifying research gaps in stress-induced metabolic regulation. The [...] Read more.
Nitraria sibirica Pall., a halophytic shrub native to arid and saline–alkaline ecosystems, represents a dual-purpose resource for ecological stabilization and functional food development. This review synthesizes current knowledge of its bioactive compounds and pharmacological properties, while identifying research gaps in stress-induced metabolic regulation. The plant contains diverse phytochemicals including phenolic glycosides (e.g., clovin), alkaloids (e.g., nitraramine), immunomodulatory polysaccharides, and anthocyanins, which collectively demonstrate superior antioxidant capacity (freeze-dried polysaccharides outperform Butylated Hydroxytoluene (BHT)), significant antihypertensive effects via angiotensin-converting enzyme (ACE) inhibition and nitric oxide (NO) pathway activation, and broad-spectrum antimicrobial activity against foodborne pathogens. Notably, its pectin components reduce allergen absorption by 72%, suggesting potential as hypoallergenic food additives. These findings validate traditional medicinal uses while revealing novel applications in functional foods and nutraceuticals. Despite promising preclinical results, key challenges remain in understanding compound synergies under environmental stress and translating findings to human applications. Future research should employ multi-omics approaches to elucidate stress-adaptive phytochemical biosynthesis, coupled with clinical validation and sustainable cultivation methods. As a model species for ecological and nutritional applications, N. sibirica offers innovative solutions for addressing both global health challenges (metabolic disorders) and environmental concerns (soil rehabilitation), positioning it at the forefront of climate-resilient agricultural innovation. Full article
(This article belongs to the Special Issue The Effect of Food Bioactive Compounds on Reducing Oxidative Stress)
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