Combating Infectious Diseases in Aquaculture

A special issue of Fishes (ISSN 2410-3888). This special issue belongs to the section "Welfare, Health and Disease".

Deadline for manuscript submissions: closed (31 July 2026) | Viewed by 1145

Editors


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Guest Editor
Fishery College, Jimei University, Xiamen 361021, China
Interests: identification of aquatic pathogens; fishery vaccine; pathologic mechanism
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Preventive Veterinary Medicine, State University of Londrina, Londrina 86057-970, Brazil
Interests: veterinary microbiology; vaccine; antimicrobial resistance; one health; rapid diagnosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Infectious diseases are a formidable challenge to the sustainability and productivity of global aquaculture, posing significant threats to economic stability, food security, and aquatic ecosystem health. Understanding the pathogens that affect aquatic species, their pathological mechanisms, host immune responses, and the complex dynamics of host–pathogen interactions is, therefore, critical for developing effective prevention, diagnostic, and control strategies.

This Special Issue aims to curate a diverse and high-quality collection of research that advances our knowledge in the critical field of aquatic animal health. We seek to bring together cutting-edge studies that delve into the etiology, diagnostics, pathology, immunology, pathogenesis, and host–pathogen relationships across a broad spectrum of farmed aquatic species. The goal is to provide a comprehensive forum for contemporary science that directly informs disease management and resilience in aquaculture.

We welcome original research articles, reviews, and perspectives that offer empirical insights, novel methodological approaches, or theoretical models. Contributions may cover, but are not limited to, emerging and re-emerging pathogens (viral or bacterial), innovative diagnostic tools, mechanisms of pathogenicity and virulence, host defense mechanisms, vaccine development, and the influence of environmental and husbandry factors on disease outbreaks. Studies focusing on both vertebrate and invertebrate aquaculture species are encouraged.

We particularly wish to inspire and showcase the work of early-career researchers and scientists dedicated to safeguarding aquatic animal health. By synthesizing current knowledge and highlighting innovative research, this Special Issue will contribute to building more robust and sustainable aquaculture practices worldwide.  We invite submissions by July 31, 2026, and will make every effort to ensure your research findings gain visibility among peers.

Prof. Dr. Songlin Guo
Prof. Dr. Ulisses De Pádua Pereira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fishes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • fishery vaccine
  • outer membrane protein
  • bacterial pathogen
  • viral pathogen
  • pathology
  • diagnostic kit
  • transcriptomic analysis

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Published Papers (1 paper)

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Research

13 pages, 34270 KB  
Communication
Susceptibility and Clinicopathological Findings in Three Amazonian Fish Species Experimentally Infected with Lactococcus spp.: A Preliminary Study
by Angélica Emanuely Costa do Rosário, Francisco Yan Tavares Reis, Angelo Carlo Chaparro Barbanti, Érik José Carvalho da Costa, Cynthia Rafaela Monteiro da Silva Maia, Suzana Kotzent, Sóstenes Apolo Correia Marcelino, Felipe Pierezan, Gustavo Moraes Ramos Valladão, Ronald Kennedy Luz, Henrique César Pereira Figueiredo, Silvia Umeda Gallani and Guilherme Campos Tavares
Fishes 2026, 11(6), 325; https://doi.org/10.3390/fishes11060325 - 29 May 2026
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Abstract
Bacterial diseases cause significant losses in the aquaculture of Amazonian fishes (Arapaima gigas, Brycon amazonicus, and Colossoma macropomum). Lactococcosis-causing bacteria (LCB) have emerged as important pathogens in global aquaculture, and although they have already been isolated from these fish [...] Read more.
Bacterial diseases cause significant losses in the aquaculture of Amazonian fishes (Arapaima gigas, Brycon amazonicus, and Colossoma macropomum). Lactococcosis-causing bacteria (LCB) have emerged as important pathogens in global aquaculture, and although they have already been isolated from these fish species, their pathogenic role remains unconfirmed. This study evaluated the susceptibility of three Amazonian fish species to Lactococcus spp. through experimental infection and performed a detailed examination of the associated pathological damage. Lactococcus formosensis, L. garvieae, and L. petauri strains were used to intracoelomically infect juvenile Amazonian fish. Following infection, the fish were monitored for 15 days to evaluate clinical signs and mortality. Clinical signs were observed in the L. garvieae-challenged A. gigas, with one fish dying at five days post-infection. The remaining experimental animals, regardless of fish species, survived the challenge. All mortalities and surviving fish at the end of the trial underwent bacteriological and histopathological examinations. Bacteriological examination confirmed bacterial re-isolation from asymptomatic animals in the L. garvieae-challenged A. gigas (2/7) and L. formosensis-challenged C. macropomum (3/7) groups using MALDI-TOF MS and multiplex qPCR analysis. No bacterial growth or histological alterations were observed in the control groups or in the groups infected with L. petauri. Microscopic examination revealed L. garvieae-induced fibrinoid-necrotic hepatitis, lymphohistiocytic myocarditis, and myositis in diseased or asymptomatic A. gigas, while L. formosensis caused lymphohistiocytic pericarditis in surviving C. macropomum. These findings provide preliminary evidence suggestive of susceptibility of A. gigas and C. macropomum to infection by L. garvieae and L. formosensis, respectively, highlighting their potential to act as asymptomatic carriers. Furthermore, the histopathological findings were suggestive of species-associated lesion patterns of piscine lactococcosis in Amazonian fish, rather than indicative of high mortality. Full article
(This article belongs to the Special Issue Combating Infectious Diseases in Aquaculture)
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