Physiological Responses of Fish to Stressors

A special issue of Fishes (ISSN 2410-3888).

Deadline for manuscript submissions: 10 June 2026 | Viewed by 1126

Special Issue Editor


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Guest Editor
School of Life Sciences, Southwest University, Chongqing 400715, China
Interests: fish; stress; physiological responses; adaptation; molecular mechanism

Special Issue Information

Dear Colleagues,

Fish, including both farmed and wild communities, are regularly subjected to various stressors. In response, they will experience a variety of physiological changes to overcome, cope with and ultimately recover from these threatening challenges. In the field of fish physiology, the response to stressors is typically initiated and regulated by hormonal systems. These systems trigger a series of events that can affect various life functions, including metabolism, immunity, behavior, growth, reproduction, development and even adaptation. This Special Issue aims to explore cutting-edge advancements in various physiological responses of fish to both natural stressors and human-derived disruptions. Submissions may take the form of original research, a full or mini-review, an opinion piece, or a meta-analysis. These submissions should address the following themes, though they are not limited to these topics:

  • Physiological responses of wild fish under human-derived interference. 
  • Physiological responses of aquatic fish under unfavorable conditions.
  • New technology, including omics, used in fish physiological responses to stressors.
  • Molecular mechanisms underlying the adaptation to various stressors.
  • Interactions between the stress axis and other physiological activities such as immunity, metabolism, development and reproduction.
  • Physiological responses of fish to stressors in a perspective of evolution. 

Dr. Xiaohong Liu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Keywords

  • wild fish
  • aquatic fish
  • physiological responses
  • new technology
  • molecular mechanisms
  • evolutionary perspectives
  • adaptation

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Published Papers (1 paper)

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Research

24 pages, 1213 KB  
Article
Adaptive Potential of Fish Species to Multiple Stressors in the Bulgarian Black Sea Environment
by Albena Alexandrova, Elina Tsvetanova, Violin Raykov, Dimitar Dimitrov and Nesho Chipev
Fishes 2026, 11(4), 191; https://doi.org/10.3390/fishes11040191 - 24 Mar 2026
Viewed by 726
Abstract
The Black Sea waters and sediments accumulate a wide range of pollutants, which, together with natural factors, can have diverse and combined effects on marine organisms. Cellular oxidative stress (OS) is a common response to environmental stressors and thus an indicator of the [...] Read more.
The Black Sea waters and sediments accumulate a wide range of pollutants, which, together with natural factors, can have diverse and combined effects on marine organisms. Cellular oxidative stress (OS) is a common response to environmental stressors and thus an indicator of the physiological resilience of organisms. The present study analyzed OS in fish species from the Bulgarian part of the Black Sea. Samples of 18 fish species were obtained during monitoring trawling in the northern and southern regions of the Bulgarian Black Sea and were analyzed. The OS-specific biomarkers (lipid peroxidation, glutathione, and antioxidant enzymes) were spectrophotometrically measured in the liver and gills. The obtained results revealed pronounced variability in pro- and antioxidant responses, shaped by sampling location, species identity, and tissue type. In fish sampled from the northern part, the liver showed stronger antioxidant activation, while the gills exhibited higher lipid peroxidation. Benthic fish exhibited pronounced hepatic antioxidant responses. Pelagic species had higher gill lipid peroxidation. Generalist feeders displayed variable stress responses associated with a diverse diet and the presence of multiple contaminants in it. In conclusion, OS was most pronounced in benthopelagic and pelagic species, which were more stressed in the northern Bulgarian part of the Black Sea, while benthic or coastal fish species experienced greater environmental pressure in the southern part. Full article
(This article belongs to the Special Issue Physiological Responses of Fish to Stressors)
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