New Discoveries and Future Perspectives: Leptin and Obesity
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 1584
Special Issue Editors
Interests: leptin; adipose tissue; obesity treatment; food intake; brown adipose tissue; obesity induced diet; drug delivery
Special Issues, Collections and Topics in MDPI journals
2. Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy
Interests: endocrinology; diabetology; obesity; hypertension; metabolic diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Twenty-five years ago, leptin, a hormone produced and secreted by adipose tissue, was discovered. From its first discovery it was identified as having a key role in the field of obesity, and was also discovered to interact with endocrine organs and physiological processes in the control of food intake and energy balance. However, due to the lack of knowledge and understanding of the molecular mechanisms responsible for its effects, the great therapeutic hopes for the involvement of leptin in the treatment of obesity suddenly vanished. Despite this, the research developed around leptin has made great contributions in the field of obesity. However, in the last few years, significant advances have been evidenced in some of the mechanisms of action responsible for effects on body weight control. All of this has meant a rejuvenated interest in this hormone, and it is believed that one day leptin could lead to much-desired therapy against obesity.
In this Special Issue, we welcome contributions related to any aspect of leptin and obesity. Our hope is that, with reference to the most recent and exciting discoveries in this scientific field, we can provide readers with an idea of the mechanisms by which leptin exerts its effects on body weight regulation, and its physiological relevance.
Dr. Marcos Carreira
Dr. Simona Frontoni
Guest Editors
Manuscript Submission Information
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Keywords
- Leptin
- blood–brain barrier
- central nervous system
- adipose tissue
- leptin resistance
- leptin transport
- hypothalamus
