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Children
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Early Interceptive Treatment of Oral Disorders: Protective Mechanisms and Future...
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Early Interceptive Treatment of Oral Disorders: Protective Mechanisms and Future Perspectives

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Dentistry & Oral Medicine".

Deadline for manuscript submissions: 20 November 2026 | Viewed by 704

Editors

Dr. Alexandru Vlasa

E-Mail Website
Guest Editor
Faculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology, 540139 Targu Mures, Romania
Interests: periodontics; periodontal disease; gingivitis; non-surgical treatment
Dr. Anamaria Bud

E-Mail Website
Guest Editor
Faculty of Dental Medicine, University of Medicine and Pharmacy, Science and Technology George Emil Palade Târgu-Mureș, 38 Gheorghe Marinescu Street, 540139 Targu Mures, Romania
Interests: palatal split; MARPE; cortico-puncture; orthodontics; orthodontic miniscrew; palatal expansion; CBCT; MSE
Dr. Massimo Corsalini

E-Mail Website
Guest Editor
Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
Interests: oral medicine; oral surgical pathology; laser application in oral surgical pathology; implant rehabilitation of oncologic patients or those affected by oral mucosa/jaw diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Oral disorders encompass varied conditions affecting teeth and surrounding tissues and represent a multifaceted aspect of overall health in children and adults. They involve various physiological and psychological processes; therefore, this Special Issue will elucidate the intricate interplay between the protective mechanisms of the body and oral disorders, such as hypo-mineralization, early childhood decay and even white spot lesions. Recent research suggests a bidirectional relationship between these, and understanding this relationship has important clinical implications. Healthcare providers should consider that comprehensive treatment strategies may yield more effective outcomes. Collaborative efforts between researchers, clinicians, and healthcare professionals are essential for advancing our understanding of this intricate interplay and enhance patient care. We invite you to contribute a research paper or review to this Special Issue.

We are soliciting the following paper types: original research; systematic review; narrative review; literature review.

Dr. Alexandru Vlasa
Dr. Anamaria Bud
Dr. Massimo Corsalini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • early childhood decay
  • hypo-mineralization
  • white spot lesions
  • early interceptive treatment
  • early orthodontics

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Published Papers (1 paper)

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Research

13 pages, 1246 KB  
Article
Orthodontic Treatment Need and Short-Term Oral Hygiene Assessment in Children Undergoing Different Early Orthodontic Treatments
by Neslihan Atmaca, Murat Tozlu, Sertaç Peker and Betül Kargül
Children 2026, 13(6), 823; https://doi.org/10.3390/children13060823 - 17 Jun 2026
Viewed by 266
Abstract
Objectives: Oral hygiene maintenance may be influenced by both malocclusion severity and orthodontic appliance type during early orthodontic treatment. Therefore, this study aimed to evaluate the relationship between orthodontic treatment need assessed using the Index of Orthodontic Treatment Need (IOTN) and oral [...] Read more.
Objectives: Oral hygiene maintenance may be influenced by both malocclusion severity and orthodontic appliance type during early orthodontic treatment. Therefore, this study aimed to evaluate the relationship between orthodontic treatment need assessed using the Index of Orthodontic Treatment Need (IOTN) and oral hygiene status measured using the Simplified Oral Hygiene Index (OHI-S) in children undergoing early orthodontic treatment and to compare short-term oral hygiene outcomes between clear aligner and removable appliance therapies. Methods: Twenty-four children aged 6–12 years with anterior dental crossbite were included in this prospective observational cohort study. Patients treated with clear aligners (n = 12) or removable appliances (n = 12) were evaluated. Orthodontic treatment need was assessed using the IOTN Dental Health Component (DHC) and Aesthetic Component (AC), and oral hygiene status was evaluated using the OHI-S at baseline and day 14. Statistical analyses were performed with p < 0.05 considered significant. Results: A statistically significant positive correlation was observed between IOTN-DHC and IOTN-AC scores (rs = 0.648; p = 0.001). Participants with higher orthodontic treatment need had poorer oral hygiene status at baseline, and this difference remained evident at day 14. Day-14 OHI-S scores were significantly higher in the removable appliance group than in the clear aligner group (p = 0.039). In addition, the reduction in OHI-S scores was significantly greater in the clear aligner group (p = 0.043). When all participants were analyzed together, oral hygiene status improved significantly from baseline to day 14 (p < 0.001). Conclusions: Higher orthodontic treatment need was associated with poorer oral hygiene status during early orthodontic treatment. Clear aligners were associated with more favorable short-term oral hygiene outcomes than removable appliances. Full article
(This article belongs to the Special Issue Early Interceptive Treatment of Oral Disorders: Protective Mechanisms and Future Perspectives)
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