Special Issue "Nuclear Transport in Ageing and Diseases"

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Nuclei: Function, Transport and Receptors".

Deadline for manuscript submissions: closed (15 November 2018)

Special Issue Editor

Guest Editor
Dr. Bor Luen Tang

Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Website | E-Mail
Interests: membrane trafficking; neuronal death and regeneration; Sirt1 and aging

Special Issue Information

Dear Colleagues,

The eukaryotic genome is physically and functionally partitioned from the rest of the cell by a nuclear envelope. A myriad of bidirectional RNA/protein transport and signalling processes between the plasma membrane-cytoplasm and the genetic blueprint-bearing nucleus occur through the nuclear pore complexes. Dynamic nuclear–cytoplasm communication underlies the physiological and homeostatic regulation of gene expression, as well as protein/organelle biogenesis in cells. Impairment of nuclear envelope integrity and nucleocytoplasmic transport processes have been implicated in a number of pathological conditions, such as aging, cardiovascular diseases, neurodegenerative disorders and cancer.

In this Special Issue of Cells, we invite your contributions, either in the form of original research articles, reviews, or shorter perspective articles on all aspects related to the theme of “Nuclear–Cytoplasmic Transport in Aging and Diseases”. Articles with mechanistic and functional insights from a cell and molecular biological perspective are especially welcome. Relevant topics include, but are not limited to

  • nuclear import and export transporters and mechanisms
  • nuclear pore complex and Nucleoporins
  • nucleocytoplasmic transport in cellular signalling
  • nucleocytoplasmic transport in aging
  • nuclear envelope and RNA/protein transport impairment in neurodegenerative disorders
  • nucleocytoplasmic transport in viral infection and diseases

Dr. Bor Luen Tang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • importins/exportins
  • lamins
  • nuclear envelope
  • nuclear pore complex
  • nucleocytoplasmic transport
  • nucleoporins

Published Papers

There is no accepted submissions to this special issue at this moment.
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