Molecular and Cellular Mechanisms of Cancers: Head and Neck Cancer

Dear Colleagues,

Head and neck cancer is a highly malignant disease, and patient`s prognosis has not substantially improved during the recent decades. Recent advances in basic research have identified the genetic background underlying head and neck squammous cell carcinomas (HNSCCs) and the molecular pathways defining the biology of HNSCC-initiating cell populations. This information is paving the path to more effective clinical treatment options based on tumor-specific molecular targeted therapies.

This Special Issue aims to explore new molecular targets for anti-HNSCC therapy, HNSCC genetics, markers for therapy success, and new synergistic drug combinations against HNSCC cells. We are curious to learn about the cellular and molecular mechanisms that determine the malignancy of HNSCC-initiating cells. This involves investigating biological parameters like tumor-initiating potential, metastatic spread, immune evasion, as well as drug vulnerability and resistance. Moreover, we are interested in the connection between biological markers that can guide clinical intervention and mechanisms underlying the oncogenic transformation caused by the human papilloma virus. Thus, we encourage scientists to contribute their research in order to improve survival and life quality of HNSCC patients.

We are delighted to present this Special Issue of Cells and hope that it will inspire head and neck cancer researchers around the world.

Prof. Holger H. Sudhoff
Dr. Felix Oppel
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.