Gastrointestinal Disease: From Cellular Mechanisms to Targeted Therapy
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 2349
Special Issue Editors
Interests: microRNA; inflammatory bowel disease; gastrointestinal cancer; intestinal permeability
Special Issues, Collections and Topics in MDPI journals
Interests: cell physiology; comparative and applied physiology; cellular homeostasis; transmembrane transport processes/systems; solute carriers (SLC); epithelial physiology; epithelial cell models; oligopeptides; immunity and inflammation; animal models; zebrafish; cytotoxicity; cell–material interactions; biomaterials; tissue engineering; tissue regeneration
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The pathophysiology of the GI tract includes a broad range of diseases and processes, from injury and repair to chronic inflammatory states and cancer. In recent years, biomedical research has aimed to characterize and elucidate the cellular mechanisms underlying GI disease progression. New technologies that focus on genomic, transcriptomic, and proteomic aspects allow us to identify the molecular mechanisms that drive disease onset and progression and thus new potential targets for therapy.
This Special Issue will aim to cover novel research exploring all cellular mechanisms, ranging from the induction of apoptosis and autophagy to cell cycle arrest, epithelial turnover, inhibition of epithelial–mesenchymal transition, suppression of cellular invasion and migration, and modulation of multiple signaling pathways in gastrointestinal disease, including cancer, immune disease, and infectious disease. Additionally, this Special Issue will include studies that highlight innovative molecular-based drug targets and their associated predictive biomarkers. Original research articles and reviews are welcome.
Dr. Grazia Serino
Dr. Amilcare Barca
Guest Editors
Manuscript Submission Information
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Keywords
- gastrointestinal cancer
- gastric cancer
- colorectal cancer
- esophageal cancer
- liver cancer
- pancreatic cancer
- inflammatory bowel disease
- miRNAs
- in vitro and in vivo models
- molecular networks
- molecular pathways
- translational medicine
- epithelial barrier functions/processes
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