Aquaporins at the Crossroads of Human Health and Disease
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 January 2026 | Viewed by 1
Special Issue Editor
Special Issue Information
Dear Colleagues,
Aquaporins (AQPs) are a family of channel proteins that facilitate the movement of water and small solutes, including glycerol, ammonia, and hydrogen peroxide across biological membranes. AQPs have emerged as crucial regulators in both human physiology and pathophysiology. Increasing evidence highlights their involvement in a broad spectrum of biological processes and diseases, spanning metabolism, inflammation, cancer, neurodegeneration, infection, and tissue remodeling.
This Special Issue of Cells seeks to gather original research articles and comprehensive reviews that advance our understanding of AQPs in health and disease. We welcome contributions exploring their structural and functional diversity, regulatory mechanisms, and roles in organ-specific pathophysiology.
Interest will be also given to studies investigating AQPs as biomarkers or therapeutic targets, as well as those employing innovative methodologies such as artificial intelligence, bioinformatics, and high-resolution imaging to dissect AQP function, distribution, and modulation.
We invite you to contribute to this interdisciplinary collection and help illuminate the expanding impact of AQPs in contemporary biomedical research.
Dr. Anna Patrizia Gena
Guest Editor
Manuscript Submission Information
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Keywords
- aquaporins
- membrane molecular transport
- channels proteins in health and disease
- novel drug targets
- cellular biophysics
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