Molecular and Signaling Pathways in Pathological Changes of Esophageal, Gastric and Intestinal Epithelial Cells and Methods of Cell Protective Treatment
Special Issue Editor
Interests: gastrointestinal physiology, gastroenterology, esophageal disorders, peptic ulcer disease, inflammatory bowel disease, ulcerative colitis, pharmacology of the gut
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue of Cells is dedicated to the changes in gastrointestinal physiology and pathology of esophageal, gastric, and intestinal epithelial cells, including cell damage, as well as the methods of protecting these cells by physiological factors and pharmacological agents.
The importance of the gastrointestinal tract (GI tract) in maintaining general health is crucial not only for normal intestinal functions, such as digestion and absorption of nutrients, which are responsible for physiological growth and development of organs but also for the proper functioning of other systems in the body, including the nervous system (brain–gut axis), cardiovascular and excretory systems, as well as acid–base balance. Maintaining the proper structure and function of these cells plays a crucial role in the integrity of the GI tract, preventing the entry of harmful substances into the body. Our goal is to provide an in-depth analysis of the various types and functions of these cells in health and disease, and to explore the involvement of multiple signaling pathways in the spectrum of diseases affecting epithelial cells that are constantly exposed to harmful stimuli. We are also interested in updating our knowledge on how these epithelial cells are protected from cellular damage in health conditions and what are the current advances in pharmacological therapy for epithelial cells of the GI tract. Original basic scientific papers, translational and clinical studies, as well as comprehensive review articles, are welcome.
Guest Editor
Prof. Dr. Tomasz Brzozowski
Guest Editor
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Keywords
- gastrointestinal epithelial cells, cellular signaling, molecular pathways, cell damage, cell protection, esophageal integrity, gastric secretion, gastric ulcer, duodenal ulcer, intestinal digestion and absorption, intestinal integrity, inflammatory bowel disease, irritable bowel syndrome, ulcerative colitis, Crohn’s Disease
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