Exploring the Interplay Between Diverse Pain Types and the Gut Microbiota: A Translational Approach

A special issue of Gastrointestinal Disorders (ISSN 2624-5647).

Deadline for manuscript submissions: 20 October 2025 | Viewed by 43

Special Issue Editors


E-Mail Website
Guest Editor

E-Mail Website
Guest Editor Assistant
Department of Biomedical Sciences, Texas A&M University School of Dentistry, Dallas, TX, USA
Interests: orofacial pain; gut–brain axis; neurobiology; single-cell sequence; multiomics

Special Issue Information

Dear Colleagues,

With the growing evidence that the gut microbiota plays a pivotal role in the pathogenesis of various diseases, its contribution to the modulation of pain has emerged as a compelling research focus. This Special Issue seeks to explore the complex interactions between different types of pain—including cancer pain, neuropathic pain, and inflammatory pain—and the gut microbiota. We welcome both basic and clinical studies that investigate the molecular mechanisms through which the gut microbiota influences pain perception and modulation, the relationship between dysbiosis and pain behaviors in animal models, and innovative therapeutic strategies based on microbiota interventions. Additionally, research on novel diagnostic tools and biomarkers linked to gut microbial pathways in pain conditions is encouraged. Our aim is to foster interdisciplinary collaboration to advance our understanding of how gut microecology contributes to pain onset, progression, and management, ultimately providing new avenues for the prevention, diagnosis, and precision treatment of pain.

Prof. Dr. Tomasz Brzozowski
Guest Editor

Dr. Ran Tao
Guest Editor Assistant

Manuscript Submission Information

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Keywords

  • gut microbiota
  • pain modulation
  • gut–brain axis
  • diagnostic biomarkers
  • microbiota-targeted therapy

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Published Papers

This special issue is now open for submission.
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