Novel Approaches in Thymic Epithelial Tumors Diagnosis and Treatment
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 22737
Special Issue Editors
Interests: Thymic epithelial tumors; thymoma; thymic carcinoma; diagnosis; biomarkers; MicroRNA; Lung carcinoma; Hematopathology
Special Issue Information
Dear Colleagues,
Epithelial thymic tumors (TET) represent a heterogeneous group of rare solid adult malignancies with unknown etiology, complex classification, and uncertain or overt malignant clinical behavior. Their classification has long been debated among pathologists due to uncertainty in the identification of neoplastic epithelial cells in the background of thymocytes, to the wide variety of rare tumors occurring in the anterior mediastinum, and to the contemporary occurrence of complex and heterogeneous autoimmune diseases. Moreover, the unique thymic immunological role and functions have been only recently discovered, and the thymus itself, in normal conditions, undergoes spontaneous atrophy from late childhood. The difficulties in TET treatment derive from their still largely unknown biology and pathogenetic mechanisms, from delayed or inadequate diagnoses, and from the rarity of expert centers and lack of standardized treatments. Significant progress in treatment of TET could be expected in the framework of expert multidisciplinary teams and of international networks, based on worldwide databases specifically dealing with these rare tumors
We hereby invite for this Special Issue of Cancers contributions describing novel molecular alterations underlying the pathobiology of TET possibly impacting epithelial cell growth and survival. In addition, manuscripts discussing developments in diagnostics or therapeutics for TET and related autoimmune diseases are also encouraged. We invite researchers to submit up-to-date original research articles, short communications, and comprehensive review articles on the topic highlighted in this Special Issue of Cancers.
Dr. Mirella Marino
Prof. Nicolas Girard
Guest Editors
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Keywords
- thymic epithelial tumors
- thymoma
- thymic carcinoma
- diagnosis
- pathology
- imaging
- surgery
- chemotherapy
- radiotherapy
- network
- biomarker
- gene expression profiling
- immunotherapy
- autoimmune disease treatment
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