Targeting Human Glioblastoma Stem-Like Cells (GSCs)

Dear Colleagues,

Glioblastoma remains a virtually incurable disease with a dismal prognosis for patients and a plethora of open questions. The current standard therapy consists of surgery, radiochemotherapy and, in some cases, the application of tumor-treating fields. Even though promising new therapeutic avenues are underway, novel and especially directed approaches are direly needed. In particular, much research in recent years showed that GBM cells can obtain a highly plastic and dynamic phenotype, which gives these cells a stem-like state that enables them to out-live conventional therapies and ultimately replenish the tumor. In order to collectively present and aggregate recent developments in precision oncology, we invite both original research and review articles highlighting key aspects of glioblastoma biology, with a special focus on stem-like cells.

Dr. Benedikt Linder
Dr. Ander Matheu
Guest Editors

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