Application of Biophysical Techniques to Cellular and Molecular Oncology

Dear Colleagues,

Dysregulated cellular processes drive malignant transformation, tumor progression, metastasis and response to therapies. Dysregulation can occur at various levels, from single molecules to cell populations. Our mechanistic understanding of these processes has been greatly advanced through interdisciplinary research that applies physical science approaches to the study of biological systems. Playing a key role in this are biophysical approaches that cross multiple spatiotemporal scales, such as microscopy, spectroscopy, single molecule methods, force measurements and molecular modeling.

In this Special Issue, we welcome both original research articles and reviews highlighting the use of biophysical techniques that provide new mechanistic insight into oncogenic processes, including but not limited to: a) DNA repair and altered transcription; b) disrupted signal transduction; c) tumor microenvironment and immune cell interactions.

Dr. Diane S. Lidke
Dr. Jennifer M. Gillette
Dr. Alessandra Cambi
Guest Editors

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