Optical Biosensor for Quantification of Biomarkers
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".
Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 5943
Special Issue Editor
Special Issue Information
Dear Colleagues,
Optical biosensors are known to be powerful tools for the quantification of biological molecules and their interactions. Optical biosensors have shown their enormous potential for diagnosis, environmental monitoring, drug development, and food safety, because of their rapid, easy-to-use, portability, multiplexity, and cost-effective diagnosis. Fluorescence, absorption, reflectance, luminescence, Raman scattering, and refractive index are the main optical transduction mechanisms used for the quantification of biomolecule interactions. Optical biosensors are widely explored for the analysis of molecular binding kinetics, biomolecules imaging, and label-free detection, and can be easily integrated with an optofluidic detection system and multiplexed with a fluorescence system, as well as plasmonic imaging and smartphone-based diagnostics.
Plasmonic nanostructures of metals by composing nanoparticles, nanoposts, nanoholes, photonic crystals, and other components, with precise control of their structural shapes and sizes, can be integrated with microfluidic settings, and are the essential components for conjugating with specific antibodies, enzymes, and DNA for the detection of a variety of diseases. Unlike electrochemical biosensors, optical biosensors provide several benefits, including electrical non-interference, sensitivity to the picomolar and femtomolar levels of molecules, being highly reproducible as a result of a unique formation of periodic nanostructures, and can be easily be a multi-modal detection unit for parallelization.
In recent years, excellent progress on optical biosensors for health monitoring has shown a great impact in health-care diagnostics. In this Special Issue, our aim is to seek extensive research efforts on optical biosensors for the quantification of biomarkers. For this issue on optical biosensor areas, we invite researchers from scientific, clinical, and engineering disciplines to submit their manuscripts.
Dr. Azahar Ali
Guest Editor
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