Aptamer-Based Biosensors for Point-of-Care Diagnostics—2nd Edition
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".
Deadline for manuscript submissions: 30 December 2026 | Viewed by 4
Special Issue Editors
Interests: electrochemical and optical sensors; graphene; nanomaterials based electrodes; bioanalysis
Special Issues, Collections and Topics in MDPI journals
Interests: biosensors; electrochemistry; cancer; aptamers; glycans
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The fast-changing fields of molecular diagnostics and personalized medicine are driving demand for innovative, rapid, and highly sensitive point-of-care (POC) technologies. Aptamer-based biosensors have become one of the most versatile and powerful options. These synthetic nucleic acid ligands provide exceptional binding precision, enabling next-generation POC devices capable of detecting a wide range of biomarkers. Their programmability, robustness, and compatibility with diverse sensing formats place them at the forefront of advances in clinical diagnostics, infectious disease monitoring, environmental analysis, and personalized healthcare.
Building on the momentum of the previous edition, this Second Edition aims to collate research that drive the field forward by exploring new concepts, technologies, and applications related to aptamer-based biosensing for POC use. We welcome contributions from researchers across multidisciplinary fields to share new advances, emerging strategies, and future perspectives. Topics of interest include, but are not limited to, the following:
- Aptamer Selection: new strategies for aptamer discovery, design, modification, and stabilization to enhance binding performance.
- Biosensor Development: innovative architectures, materials, and fabrication techniques, including wearable technologies, microfluidic platforms, paper-based diagnostics and lab-on-a-chip technologies.
- Detection Techniques: advances in signal transduction mechanisms such as electrochemical, optical, and mass-sensitive approaches.
- Translational and Field Applications: demonstrations of aptamer-based biosensors in real-world POC scenarios, including clinical diagnostics, infectious disease management, environmental monitoring, and personalized medicine, highlighting pathways toward practical implementation and commercialization.
We look forward to your valuable contributions to this Second Edition, which will continue to advance the frontier of aptamer-based biosensing and support the development of impactful point-of-care diagnostic solutions.
Prof. Dr. Cecilia Cristea
Dr. Ana Díaz-Fernández
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- aptamer
- biosensor
- point-of-care
- SELEX
- diagnostics
- precision medicine
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