Single-Molecule Protein Dynamics

Dear Colleagues,

Proteins play a critical role in maintaining every aspect of cell survival and metabolism. The inherent dynamics of proteins in their native functional state, as well as when folding/unfolding and forming interactions, results in an ensemble of protein molecules with distinct conformational states. The dynamic conformational populations and transitions between conformational states, which have been found to be closely related to protein function and regulation, are often challenging to explore by bulk techniques. Single-molecule techniques, including both fluorescence-based and force-based approaches, have been developed as powerful tools to investigate the conformational dyamics of proteins and provide mechanistic insights into the working mechanisms of biomolecules at single-molecule resolution.

This Special Issue on “Single-Molecule Protein Dynamics” calls for manuscripts applying or developing single-molecule approaches to investigate the dynamics of the structure, folding, and interactions of proteins, furthering a deeper understanding of how proteins function in biological processes.

Dr. Si Wu
Prof. Dr. Sarah Perrett

Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.