Phytochemical Constituents of Medicinal Plants for the Treatment of Inflammatory Disease 2021
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Natural and Bio-derived Molecules".
Deadline for manuscript submissions: closed (20 December 2022) | Viewed by 23090
Special Issue Editors
Interests: diabetic complications; NASH; IBD; Toll-like receptor signal pathway; innate immunity
Special Issues, Collections and Topics in MDPI journals
Interests: network pharmacology; multicompounds-multitargets effects; AI-based drug-target interaction prediction
Interests: telomere; telomerase; aging; hepatocellular carcinoma; metastasis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Plant-derived phytochemicals have emerged as novel agents for protecting against chronic disorders. Owing to the diversity of phytochemicals, they cover a wide spectrum of therapeutic indications against various inflammation-related diseases, such as cancer, inflammation, cardiovascular, rheumatoid, autoimmune, and neurological disease, and have been a productive source of lead compounds for the development of novel medications. Recently, efforts to understand the disease by integrating conventional molecular biological experiments, bio-big data analysis, and AI technologies have increased rapidly. In order to know the polypharmacological effects of multicomponents, a lot of time and effort is required only through conventional experiments. Therefore, it is possible to develop a deeper understanding of the disease and better treatments through a more integrated approach.
An important direction for future investigation is to further optimize integrated phytochemical analysis and network pharmacology to predict multitargets. Combinatorial strategies which target multiple mechanisms, such as increasing anti-inflammatory efficacy and triggering a response of innate immune systems controlling chromosome stability, may offer a better chance for clinically meaningful treatment. This Special Issue aims to identify lead compounds for inflammation-related diseases through in-depth mechanism studies of medicinal plant components. The studies on complex mixtures of natural products must focus on specific compounds in regards to the pharmacological properties of the mixture.
Dr. Ki Sung Kang
Dr. Ik-Hyun Cho
Dr. Chang-Eop Kim
Dr. Young-Joo Kim
Guest Editors
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Keywords
- Bioactive natural compounds
- Innate immunity
- Inflammatory-related diseases
- Telomere and telomerase
- Metastasis
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