Poly-Pharmacological Approaches for Evaluating Targets with Multiple Antioxidative Mechanisms of Phytochemicals
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Methods for Antioxidants Evaluation/Measurement".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 6848
Special Issue Editors
Interests: diabetic complications; NASH; IBD; Toll-like receptor signal pathway; innate immunity
Special Issues, Collections and Topics in MDPI journals
Interests: diabetes; obesity; NASH; inflammation; Toll-like receptor signal pathway
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Plant-derived phytochemicals act as antioxidants. Owing to their diversity, phytochemicals cover a wide spectrum of therapeutic indications against various oxidative-stress-related diseases, such as cancer, cardiovascular, autoimmune, and neurological diseases; additionally, they have been a productive source of lead compounds for the development of novel medications. However, in the study of the various mechanisms of action of phytochemicals, there are many difficulties with existing research techniques. If we are to build our understanding of the poly-pharmacological effects of phytochemicals only through conventional experiments, a lot of time and effort is required. Recently, efforts to understand the disease by integrating conventional molecular biological experiments, bio-big-data analysis, and AI technologies have been rapidly increasing. Therefore, it is possible to develop a deeper understanding of the disease and to develop better treatments through a more integrated approach. An important direction for future investigation is to further optimize integrated phytochemical analyses with molecular biological, systems biological, and network pharmacological approaches so that we can predict multiple targets. This Special Issue aims to identify the molecular targets and mechanisms of phytochemicals for oxidative-stress-related diseases through poly-pharmacological approaches.
Dr. Ki Sung Kang
Dr. Dahae Lee
Guest Editors
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Keywords
- phytochemicals
- antioxidants
- oxidative stress
- molecular biology
- systems biology
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