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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Preclinical Evaluation of Biomaterials and Medical Devices for the Musculoskeletal System

edited by

Silvia Brogini

and Matilde Tschon

submission deadline 31 May 2026 | 1 articles | Viewed by 4110 | Submission Open

Keywords: biomaterials and medical devices; preclinical testing; humanized advanced in vitro models; orthopaedic applications

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Application of Bioengineering to Clinical Orthodontics—2nd Edition

edited by

Zhiyi Shan

and

Yanqi Yang

submission deadline 31 May 2026 | 1 articles | Viewed by 3286 | Submission Open

Keywords: biomechanics; biomaterials; tissue engineering; orthodontics; craniofacial regeneration; computer-aided diagnosis; AI used in craniofacial fields

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Nano–Bio Interface—Second Edition

edited by

Zicheng Deng

Donglu Shi

and

Yilong Wang

submission deadline 31 May 2026 | 3 articles | Viewed by 2923 | Submission Open

Keywords: nanoparticles; nanotoxicology; drug delivery; tissue engineering; diagnostics; environmental health

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Artificial Intelligence in Biomedical Engineering Applications Towards Clinical Translation

edited by

Shivaram Poigai Arunachalam

submission deadline 31 May 2026 | 3 articles | Viewed by 2475 | Submission Open

Keywords: artificial intelligence (AI); bioengineering; clinical translation; medical imaging; digital twins; precision medicine; digital health; explainable AI (XAI)

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Three-Dimensional Culture Systems: Bridging Biology and Medicine

edited by

Fatima A. Merchant

submission deadline 31 May 2026 | 1 articles | Viewed by 2423 | Submission Open

Keywords: 3D culture platforms; microengineered 3D systems; biomaterials for 3D culture; engineering complex 3D microenvironments; 3D systems for modeling disease and physiological processes; 3D culture-based therapies and diagnostic tools; translation of 3D systems for clinical applications

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Development of Biocatalytic Processes and Green Energy Technologies

edited by

Federico Zappaterra

Pier Paolo Giovannini

and

Lindomar Alberto Lerin

submission deadline 31 May 2026 | 1 articles | Viewed by 1771 | Submission Open

Keywords: sustainable biocatalysis; enzymatic process and scale up; bio-based polymers; hybrid chemo-biotechnologies; green energy conversion

(This special issue belongs to the Section Biochemical Engineering)

Application of Bioengineering to Orthopedics

edited by

Simon Kwoon-ho Chow

and

Stuart Goodman

submission deadline 31 May 2026 | 1 articles | Viewed by 1677 | Submission Open

Keywords: orthopaedics; biomechanics; biomaterials; tissue engineering; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Intelligent Health Management and Rehabilitation Technology: Integrating Large Language Models and AI Solutions

edited by Ning Deng

submission deadline 31 May 2026 | 3 articles | Viewed by 1458 | Submission Open

Keywords: intelligent rehabilitation technology; health monitoring systems; machine learning in healthcare; intelligent nursing technology; proactive health management; large language models in healthcare; AI-assisted clinical decision-making; personalized rehabilitation strategies

(This special issue belongs to the Section Biosignal Processing)

Applications of Transcranial Stimulation and EEG-Based Feedback Systems in Bioengineering

edited by Milan Pantovic and

Brach Poston

submission deadline 31 May 2026 | 1 articles | Viewed by 919 | Submission Open

Keywords: non-invasive brain stimulation; performance optimization; EEG-based feedback systems; wearable neuromodulation; virtual reality integration

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Intelligent Systems: From Robotic Manipulation to AI-Driven Healthcare Solutions

edited by

Tae-Seong Kim

submission deadline 31 May 2026 | 1 articles | Viewed by 560 | Submission Open

Keywords: intelligent robotics; medical AI; robotic manipulation; healthcare automation; machine learning in biomedicine; surgical robotics; Bio-inspired systems; AI-driven diagnostics.

(This special issue belongs to the Section Biosignal Processing)

New Sights of Data Analysis and Digital Model in Biomedicine

edited by

Robert Karpiński

submission deadline 31 May 2026 | Viewed by 530 | Submission Open

Keywords: artificial intelligence in medicine; machine learning for diagnosis; deep learning in medical imaging; predictive analytics in healthcare; AI-powered clinical decision support; natural language processing in biomedicine; data-driven disease diagnosis; digital twins in healthcare; big data in biomedical diagnostics; AI-enhanced biomarker discovery

(This special issue belongs to the Section Biosignal Processing)

Applied Biomechanics in Rehabilitation and Ergonomics

edited by Márcio Goethel

submission deadline 31 May 2026 | 1 articles | Viewed by 424 | Submission Open

Keywords: musculoskeletal; biomechanics; rehabilitation; ergonomics

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Therapeutic Solutions for Pain

edited by Farah Deba and

Olga Kopach

submission deadline 31 May 2026 | Viewed by 382 | Submission Open

Keywords: tissue engineering; cell therapy; drug discovery; chronic pain; biomaterials; drug delivery; nanotechnology; pain signaling

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Advancing Theranostics Through Photodynamic Therapy

edited by Taokun Luo and Wenyao Zhen

submission deadline 31 May 2026 | Viewed by 342 | Submission Open

Keywords: photodynamic therapy (PDT); theranostics; photosensitizers; light delivery systems; real-time imaging; targeted therapy; personalized medicine; translational research

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Next-Generation Neurodiagnostics: Deep Learning, Hyperspectral Imaging, and Computing Acceleration in Brain Condition Detection

edited by

Miguel Chavarrías

César Sanz

and Jaime Sancho

submission deadline 31 May 2026 | Viewed by 233 | Submission Open

Keywords: hyperspectral imaging; multimodal imaging; neurodiagnostics; deep learning; machine learning; accelerated computing

(This special issue belongs to the Section Biosignal Processing)

Advancing Spinal Instability Diagnosis with Artificial Intelligence

edited by

John Hipp

submission deadline 31 May 2026 | Viewed by 208 | Submission Open

Keywords: spine; lumbar; cervical; thoracic; instability; stability; diagnosis; medical imaging; degenerative; trauma; intervertebral motion; spinal alignment; loss of motion segment integrity

(This special issue belongs to the Section Biosignal Processing)

Multimodal Neuroimaging Techniques: Progress and Application, Second Edition

edited by Frédéric Grouiller

submission deadline 31 May 2026 | Viewed by 171 | Submission Open

Keywords: multimodal neuroimaging; MRI; MEG; EEG; fNIRS; PET; TMS; VR technology; imaging setups; brain function; multimodal signals processing; deep learning algorithms; artificial intelligence; brain computer interface

(This special issue belongs to the Section Biosignal Processing)

Novel MRI Techniques and Biomedical Image Processing: Second Edition

edited by Dilbag Singh

submission deadline 31 May 2026 | Viewed by 155 | Submission Open

Keywords: MRI; image generation; image processing; image acquisition; image reconstruction; machine learning; deep learning

(This special issue belongs to the Section Biosignal Processing)

Advances in Neural Interface Techniques and Applications

edited by

Lei Chen

and

Yi Wang

submission deadline 31 May 2026 | Viewed by 90 | Submission Open

Keywords: neural interface; brain machine interface; neural recording and stimulation; neural signal processing; flexible electronics; implantable bioelectronics; surgical implantation; neural prosthetics; neurological diseases and treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Harnessing Microbes for Bioproduction: From Synthetic Biology to Bioprocess Scale-Up

edited by

Edmar Oliveira-Filho

Linda Guaman

Carlos Barba-Ostria

and Luiziana Ferreira Da Silva

submission deadline 31 May 2026 | Viewed by 88 | Submission Open

Keywords: synthetic biology; metabolic engineering; enzyme engineering; bioproducts; biomanufacturing; bioprocess engineering; chemical engineering

(This special issue belongs to the Section Biochemical Engineering)

Electromyography Techniques for Motion Analysis

edited by

Gabriel Delgado-Garcia

, Naiquan (Nigel) Zheng and

Alejandro Molina-Molina

submission deadline 31 May 2026 | Viewed by 62 | Submission Open

Keywords: electromyography; surface electromyography; muscle electromyography; motion analysis; postural control and balance; kinematics; kinetics; inertial measurement units; biplane fluoroscopy; gait analysis; clinical applications; musculoskeletal disorders; musculoskeletal diseases; injury biomechanics; sport medicine; sport performance; quality of life

(This special issue belongs to the Section Biosignal Processing)

Injectable Hydrogels and Smart Biomaterials for Precision Regenerative Therapy

edited by

Prakash Gangadaran

submission deadline 31 May 2026 | Viewed by 32 | Submission Open

Keywords: injectable hydrogels; smart biomaterials; regenerative medicine; precision therapy; stimuli-responsive materials; tissue engineering; drug delivery; biocompatibility; stem cell encapsulation; translational nanomedicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Human Performance: Advanced Monitoring and Intervention Technologies in Sports Science

edited by

Jorge Morais

submission deadline 31 May 2026 | Viewed by 22 | Submission Open

Keywords: sports technology; athlete development; wearable sensors; performance analysis; biomechanics; artificial intelligence; machine learning; data analytics; virtual reality; training optimization

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Multiscale Computational Biomechanics and AI

edited by

Ramana Pidaparti

Jinxiang Xi

and Israr Ibrahim

submission deadline 31 May 2026 | Viewed by 16 | Submission Open

Keywords: multiscale biomechanics; computational modeling; machine learning in bioengineering; tissue mechanics; finite element analysis; AI in biomechanics; physics-informed neural networks (PINNs); markerless motion capture; generative AI; digital twin; biomechanical simulation; biofluid dynamics; mechanobiology; personalized medicine; biomedical applications

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Anaerobic Biotechnologies for Energy and Resource Recovery from Waste

edited by

Abid Hussain

and Kaushik Venkiteshwaran

submission deadline 31 May 2026 | Viewed by 8 | Submission Open

Keywords: anaerobic digestion; bioelectrochemical systems; solid-state fermentation; waste-to-energy conversion; resource recovery; biogas; SCFAs; microbial electrosynthesis; circular bioeconomy; organic waste valorization

(This special issue belongs to the Section Biochemical Engineering)

Artificial Intelligence in Bioengineering: Innovations, Challenges, and Future Directions

edited by

Daniele Giansanti

submission deadline 31 May 2026 | Submission Open

Keywords: artificial intelligence; bioengineering; machine learning; biomedical imaging; precision medicine; digital twins; biomedical devices; explainable AI; drug discovery; multi-omics integration

(This special issue belongs to the Section Biosignal Processing)

Advanced Biofabrication for Next-Generation Biomedical Devices and Tissues

edited by

Changchun Zhou

submission deadline 31 May 2026 | Submission Open

Keywords: 3D bioprinting; biofabrication; tissue engineering; biomedical devices; additive manufacturing; regenerative medicine; smart biomaterials

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Advances in Additive Manufacturing Technologies in the Clinical, Pharmaceutical and Biomedical Sectors—Second Edition

edited by

Karthik K. Tappa

submission deadline 31 May 2026 | Submission Open

Keywords: 3D printing; bioprinting; bioactive materials; bioink; anatomical models; surgical guides; patient-specific implants; 3D-printed drug delivery systems; 3D-printed biomedical devices

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Extracellular Matrix Biomaterial for Tissue Engineering and Regenerative Medicine, 2nd Edition

edited by Elizabeth C. Martin and

Jorge Alfonso Belgodere

submission deadline 31 May 2026 | Submission Open

Keywords: extracellular matrix; ECM protein; biomaterials; 3D bioprinting; tissue engineering; regenerative medicine

(This special issue belongs to the Section Regenerative Engineering)

Advancements in Biomechanical Gait Analysis: Implications for Footwear Biomechanics and Sports Injury Prevention

edited by

Yang Song

Dong Sun

and

Xuanzhen Cen

submission deadline 30 Jun 2026 | 2 articles | Viewed by 9822 | Submission Open

Keywords: human locomotion; motion capture technology; wearable sensors; biomechanical modeling; injury risk assessment; personalized footwear design; machine learning in biomechanics; sports science integration

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advanced Wearable Sensors for Human Gait Analysis

edited by

Tong Li

, Qingguo Li and Bingfei Fan

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3573 | Submission Open

Keywords: wearable sensors; human movement analysis; rehabilitation; sport science; sensor fusion; machine learning

(This special issue belongs to the Section Biosignal Processing)

Advances in Computational Imaging and Artificial Intelligence for Biomedical and Clinical Applications

edited by Nan Meng,

Jason Pui Yin Cheung

and Junming Shao

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2685 | Submission Open

Keywords: computational imaging; artificial intelligence; deep learning; medical image analysis; medical diagnosis

(This special issue belongs to the Section Biosignal Processing)

Novel Strategies in Dentin/Pulp Regeneration Through Tissue Engineering

edited by Roda Seseogullari-Dirihan

submission deadline 30 Jun 2026 | Viewed by 237 | Submission Open

Keywords: dentin/pulp regeneration; stem cell; tissue engineering; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

The Biophysics of Vocal Onset, 2nd Edition

edited by

Sten Ternström

and

Claudia Manfredi

submission deadline 30 Jun 2026 | Viewed by 167 | Submission Open

Keywords: biophysics; vocal onset; intraglottal pressure; transglottal flow; glottal area; intraglottal turbulence; videokymography; glottography; high-speed imaging; voice acoustics; voice synthesis; machine learning

(This special issue belongs to the Section Biosignal Processing)

Innovative Bioengineering Platforms for Cancer Therapeutics: From Models to Screening

edited by

Eriko Katsuta

submission deadline 30 Jun 2026 | Viewed by 27 | Submission Open

Keywords: cancer drug screening; tumor microenvironment; 3D culture/organoids; microfluidics/organ-on-a-chip; AI-based drug discovery; bioinformatics and modeling; precision oncology; systems biology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomechanics and Motion Analysis, Second Edition

edited by

Christina Zong-Hao Ma

and

Hong Fu

submission deadline 30 Jun 2026 | Viewed by 14 | Submission Open

Keywords: biomechanics; motion capture and analysis; sports and rehabilitation engineering; artificial intelligence; assistive technology

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Application of Intelligent Diagnosis and Decision Support in Biomedical Engineering

edited by

Voula Georgopoulos

and

Chrysostomos Stylios

submission deadline 30 Jun 2026 | Submission Open

Keywords: clinical decision support; computational diagnostics; explainable artificial intelligence (XAI); healthcare technology; integrated diagnostic platforms; machine learning; predictive modeling; wearable technology

(This special issue belongs to the Section Biosignal Processing)

Contactless Technologies for Patient Health Monitoring

edited by

Mark van Gastel

, Wim Verkruysse,

Xi Long

and Rick Bezemer

submission deadline 30 Jun 2026 | Submission Open

Keywords: contactless monitoring; unobtrusive sensing; physiological measurements; contextual monitoring; clinical decision support

(This special issue belongs to the Section Biosignal Processing)

Biomedical Engineering for Facial Reconstruction

edited by James F. Thornton

submission deadline 30 Jun 2026 | Submission Open

Keywords: facial reconstruction; biomedical engineering; dermal regeneration templates; biodegradable temporizing matrix (BTM); integra dermal regeneration matrix; tissue engineering; biomaterials; wound healing; soft tissue regeneration; vascularization; reconstructive surgery innovation; personalized medicine; hyperbaric oxygen treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Nanoparticle-Based Drug Delivery Systems for Cancer Therapy

edited by Tianzhu Zhang and

Qiaoyu Liu

submission deadline 30 Jun 2026 | Submission Open

Keywords: biomaterials; biomedical engineering; nanomedicines; drug delivery; cancer therapy

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Novel Microfluidics Applications in Dental, Oral, and Craniofacial Research

edited by

Xianrui Yang

, Jing Pan, Fan Zhang and

L. Shannon Holliday

submission deadline 3 Jul 2026 | Viewed by 174 | Submission Open

Keywords: dentistry; microfluidics; stem cells; bioengineering; biological mechanisms

Advancements in Artificial Intelligence for Wearable Devices: A New Perspective on Healthcare Applications—2nd Edition

edited by

Maria Giovanna Bianco

Syed Kamrul Islam

and

Salvatore Pullano

submission deadline 31 Jul 2026 | Viewed by 56 | Submission Open

Keywords: wearable devices; artificial ilntelligence; machine learning; biomedical signal processing; deep learning; bio-inspired systems; biosensor devices

(This special issue belongs to the Section Biosignal Processing)

Advances in Functional Brain Research Using Multimodal and Integrative Techniques

edited by

Stefania Coelli

, Eleonora Maggioni, Letizia Squarcina and

Augusto Bonilauri

submission deadline 31 Jul 2026 | Submission Open

Keywords: EEG; MEG; fMRI; fNIRS; SEEG; Multimodal imaging; data integration; physiological parameters

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Machine Learning and Explainable Artificial Intelligence in Biomedical Data Mining, and Disease Diagnosis Frameworks—2nd Edition

edited by

Amad Zafar

submission deadline 31 Jul 2026 | Submission Open

Keywords: EEG; fNIRS; MRI; X-rays; biomedical signal and image processing; machine learning; explainable artificial intelligence; biomedical data mining; computer-aided diagnosis; brain– computer interfaces; healthcare

(This special issue belongs to the Section Biosignal Processing)

AI and Data Analysis in Neurological Disease Management

edited by

Bess Lam

and

Ka-Chun Wong

submission deadline 31 Aug 2026 | 2 articles | Viewed by 642 | Submission Open

Keywords: AI technologies; management of neurological diseases; interdisciplinary approaches; data analysis

(This special issue belongs to the Section Biosignal Processing)

Development of Predictive Models for Ocular Injuries in Athletes Using Computational Biomechanics

edited by

Reza Razaghi

submission deadline 31 Aug 2026 | Viewed by 42 | Submission Open

Keywords: computational biomechanics; ocular trauma; sports injuries; finite element modeling; predictive modeling; eye protection; ocular tissue mechanics; sports medicine

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Extracellular Vesicles: From Basic Research to Therapeutics

edited by Yan Li

submission deadline 31 Aug 2026 | Viewed by 24 | Submission Open

Keywords: extracellular vesicles; bioreactors; cell– cell interactions; bioengineering; multi-omics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Intervertebral Disc Models: From Basic Science to Clinical Practice

edited by Lidija Gradišnik

submission deadline 10 Sep 2026 | Viewed by 214 | Submission Open

Keywords: intervertebral disc; disc degeneration; cell isolation; cell cultures; in vitro cell models; 3D bioprinting; treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Oral and Maxillofacial Regeneration and Restoration

edited by

Soo-Hwan Byun

Byoung-Eun Yang

and

Sang-Yoon Park

submission deadline 31 Oct 2026 | Viewed by 1 | Submission Open

Keywords: bone regeneration; tissue regeneration; digital dentistry; customized restoration; oral and maxillofacial reconstruction

(This special issue belongs to the Section Regenerative Engineering)

Soft Tissue Reconstruction and Repair

edited by

Michalis P. Katsimpoulas

submission deadline 31 Oct 2026 | Submission Open

Keywords: vascularization; soft tissue reconstruction; biomaterials; tissue engineering; hydrogels

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Displaying special issue 301-350 on page 7 of 8.

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