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Microfluidic Devices and Systems in Biomedical Research

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 May 2026 | Viewed by 6

Special Issue Editors


E-Mail Website
Guest Editor
Center for MicroElectroMechanical Systems (CMEMS), University of Minho, Campus Azurém, 4800-058 Guimarães, Portugal
Interests: microfluidics systems; nanoparticles; lab-on-a-chip; 3D manufacturing; microdevices
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Center for Microelectromechanical Systems (CMEMS-UMinho), University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal
Interests: lab-on-a-chip; optical microdevices; integrated optics; sensors and actuators; spectrophotometry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Microfluidic and lab-on-a-chip (LOC) technologies have rapidly evolved since the introduction of the first micro-total analysis system (μTAS) in the 1990s. Over the past three decades, substantial progress has been made in areas such as microfabrication, fluid control at the microscale, biosensing, and bioprinting.

These advances have been further amplified by the integration of sophisticated optical, acoustic, magnetic, thermal, and electrochemical microsensors and microactuators, leading to systems with enhanced functionality, miniaturization, and versatility. Such developments have transformed diagnostics, biomedical research, environmental monitoring, and even enabled novel applications in fields such as the aerospace industry. In recent years, organ-on-a-chip (OoC) platforms have emerged as a groundbreaking extension of LOC systems. These devices mimic the structural and functional complexity of living tissues and organs, enabling more accurate modelling of human physiological and pathological conditions in a controlled, chip-based environment.

This Special Issue welcomes high-quality contributions—including original research articles, review papers, and brief communications—that showcase the latest innovations and challenges in microfluidic systems. Topics of interest include, but are not limited to, microfluidic device development, organ-on-a-chip systems, microfabrication techniques, advanced sensing and actuation technologies, and computational modelling of microscale phenomena.

Dr. Vera Faustino
Dr. Susana O. Catarino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microfluidics
  • lab-on-a-chip
  • organ-on-a-chip
  • microfabrication
  • biosensing
  • microactuators
  • biomedical engineering
  • point-of-care diagnostics
  • microsystems integration
  • multiphysics modelling

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Published Papers

This special issue is now open for submission.
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