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Deep Learning in Medical Image Analysis: Progress and Challenges

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Computing and Artificial Intelligence".

Deadline for manuscript submissions: 30 October 2025

Special Issue Editors

College of Optoelectronic Engineering, Chongqing University, No. 174, Shazheng Street, Shapingba District, Chongqing 400044, China
Interests: computational pathology; medical image processing; AI for healthcare; XAI; multimodal learning

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Guest Editor
Department of Medicine and Health Sciences “Vincenzo Tiberio”, University of Molise, 86100 Campobasso, Italy
Interests: medical image processing; XAI; multimodal learning
Special Issues, Collections and Topics in MDPI journals
Center of Digital Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China
Interests: medical image processing; dental image reconstruction

Special Issue Information

Medical images are the most important data modality in medical diagnosis, treatment, prognosis, and medical research. Traditional recognition, detection, segmentation, and reconstruction methods for medical images based on manual feature extraction and machine learning have come a long way, and their inefficient and poorly task-matched feature representations have become bottlenecks for development. With the emergence of deep learning, a good solution to this problem has arised in end-to-end representation learning. However, existing deep learning-based medical image analysis methods suffer from difficult annotations, few samples, missing modalities, and the black-boxing of models, which leads to a certain gap between them and practical clinical applications. This Special Issue covers the following topics, but it is not limited to them:

  1. Multimodal representation learning in medical image analysis;
  2. Unsupervised domain adaptation for medical image analysis;
  3. Meta-learning and medical image analysis;
  4. Deep clustering for medical image recognition;
  5. Interpretable deep learning for medical image analysis;
  6. Weakly supervised representation learning for medical image analysis;
  7. The analysis and representation of high-dimensional tensors for medical image analysis.

 

Dr. Pan Huang
Prof. Dr. Francesco Mercaldo
Dr. Sukun Tian
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • medical image analysis
  • deep learning
  • multimodal representation learning
  • unsupervised domain adaptation
  • meta-learning
  • deep clustering
  • interpretable deep learning
  • weakly supervised representation learning
  • high-dimensional tensors

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Published Papers

This special issue is now open for submission.
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