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Biological Activities of Plant Extracts and Their Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".

Deadline for manuscript submissions: 20 July 2025 | Viewed by 1203

Special Issue Editor


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Guest Editor
Departmento of Biotechnology, Metropolitan Autonomous University, Iztapalapa Campus, Av. Ferrocarril de San Rafael Atlixco 186, México City 09310, Mexico
Interests: plant cell cultures; secondary metabolites; biological activity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plants are an abundant source of specialized metabolites that play roles in plant growth and survival. The effects of secondary metabolites on the interactions between plants with microorganisms or other organisms are relevant for obtaining compounds with biological activity. Scientific advances in the isolation, obtaining, identification, and evaluation of the biological activities of secondary metabolites are one way to determine their applications. This Special Issue on “Biological Activities of Plant Extracts and Their Applications” aims to evaluate the current state of the art in the study of secondary metabolites and their application due to their biological activity. 

We invite authors to submit original research articles and review articles covering (but not limited to) the following topics: the biological activity of plant extracts and their applications and the biological activity of extracts from plant cell cultures and their applications.

Prof. Dr. Francisco Cruz-Sosa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biological activity
  • bioactive compounds
  • plant cell cultures
  • plant extracts
  • secondary metabolites

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Published Papers (1 paper)

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Research

12 pages, 1310 KiB  
Article
Residues of St. John’s Wort (Hypericum perforatum) Tea Infusions/Water Extracts as a Valuable Source of Tocotrienols: An Extraction Study
by Inga Mišina, Ingus Perkons, Aleksander Siger, Arianne Soliven and Paweł Górnaś
Appl. Sci. 2025, 15(4), 2047; https://doi.org/10.3390/app15042047 - 15 Feb 2025
Cited by 3 | Viewed by 668
Abstract
Hypericum perforatum L., commonly known as St. John’s wort, is a widely distributed herbaceous plant utilized in traditional and phytomedicinal applications, particularly for its hydrophilic bioactive compounds. It is often used for treating early depressive states. In this study, we focused on reporting [...] Read more.
Hypericum perforatum L., commonly known as St. John’s wort, is a widely distributed herbaceous plant utilized in traditional and phytomedicinal applications, particularly for its hydrophilic bioactive compounds. It is often used for treating early depressive states. In this study, we focused on reporting the tocotrienols—lipophilic phytochemicals with health-promoting properties—in St. John’s wort. H. perforatum flowerheads predominantly contained tocotrienols compared with tocopherols (54 and 30 mg/100 g dry weight, respectively). The major tocotrienols (T3) were δ-T3 and α-T3 (34.0 and 17.6 mg/100 g dry weight, respectively). Tocopherols and tocotrienols are lipophilic phytochemicals that cannot be present in St. John’s wort water extracts (tea infusions), but they can be recovered from the remaining residues of H. perforatum tea infusions by using hydroethanolic solutions. A 50.0% (v/v) hydroethanolic solution was not effective in the recovery of tocochromanols. The greatest increase in the extractability of tocochromanols was observed for 70.0–80.0% (v/v) hydroethanolic extracts, while increasing the ethanol concentration from 90.0% to 96.2% (v/v) only slightly improved extractability (not statistically significant). For each ethanol concentration, the recovery was proportionally higher for tocotrienols than for tocopherols. Residues of H. perforatum tea infusions can be proposed as valuable by-products rich in tocotrienols. Full article
(This article belongs to the Special Issue Biological Activities of Plant Extracts and Their Applications)
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