Advances in Ovarian and Testicular Physiology

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Reproduction".

Deadline for manuscript submissions: closed (10 January 2025) | Viewed by 1365

Special Issue Editor


E-Mail Website
Guest Editor
1. Undergraduate Course in Biological Sciences, Parnaíba Delta Federal University, 2819, São Sebastião Avenue, Parnaíba 64202‑020, PI, Brazil
2. Graduate Program in Biotechnology (PPGBiotec), Parnaíba Delta Federal University, 2819, São Sebastião Avenue, Parnaíba 64202‑020, PI, Brazil
3. Graduate Program in Physiological Sciences (PPGCF), Higher Institute of Biomedical Sciences (ISCB), State University of Ceará (UECE), Dr. Silas Munguba Avenue, 1700, Fortaleza 60714‑903, CE, Brazil
4. Graduate Program in Biotechnology (PPGB), Federal University of Ceara, 100, Comandante Maurocélio Rocha Ponte Avenue, Sobral 62041‑040, CE, Brazil
Interests: folliculogenesis; oocyte development; follicle growth; preantral follicles; metaphase II, spermatogenesis; Leydig cells; Sertoli cells; seminiferous tubule; reproduction

Special Issue Information

Dear Colleagues,

Several advances have been observed regarding knowledge about reproductive physiology. However, the challenges are still many, whether due to the need to improve biotechnologies of reproduction that serve survivors of gonadotoxic diseases, such as cancer, or due to the need to produce or preserve animal genetic resources, such as those of high zootechnic value or endangered animals. In any of these situations, we still have a long way to go.

The aim of this Special Issue entitled “Advances in Ovarian and Testicular Physiology” is to compile the main advances related to promising alternatives for maintaining or improving reproductive potential in male and female mammals.

Therefore, we are pleased to invite you to submit your latest findings from in vivo or in vitro experiments testing different synthetic or natural substances or supplements, physical exercise or diet protocols, and alimentary supplements, all considering their therapeutic potential to improve or potentialize ovarian or testicular cell survival and development, focusing on gonadal health.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: animal reproduction physiology.

Prof. Dr. Valdevane Rocha Araújo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • early folliculogenesis
  • antral follicles
  • oocyte maturation
  • spermatozoa
  • epididymis
  • antioxidants
  • culture media composition
  • anabolic steroids
  • high-fat diet
  • physical activity

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

22 pages, 6636 KiB  
Article
Semen Quality, Testicular Cell Apoptosis, and Transcriptome Analysis Following Mild Scrotal Heat Stress in Wugu–Hu Crossbred and Hu Rams
by Shikun Chen, Mingxu Jiang, Yanyun Wang, Qingjie Pan, Henry Annandale, Peter Charles Irons and Huansheng Dong
Animals 2025, 15(5), 724; https://doi.org/10.3390/ani15050724 - 3 Mar 2025
Viewed by 838
Abstract
Hu and Wugu × Hu rams underwent scrotal insulation to simulate mild heat stress, resulting in a 3.0 ± 0.1 °C increase in scrotal surface temperature. Semen samples were collected every five days from day 11 to 56, and testis samples immediately after [...] Read more.
Hu and Wugu × Hu rams underwent scrotal insulation to simulate mild heat stress, resulting in a 3.0 ± 0.1 °C increase in scrotal surface temperature. Semen samples were collected every five days from day 11 to 56, and testis samples immediately after insulation. Both breeds experienced similar semen quality reductions and recovery trends, including reduced motility, concentration and the percentage of morphologically normal, but on days 41 and 46, Wugu–Hu rams exhibited significantly lower sperm motility than Hu rams (p < 0.05). Wugu–Hu rams demonstrate more transcriptomic changes. Further GO analysis revealed enrichment in spermatogenesis-related processes, while KEGG analysis identified Oocyte meiosis and cell cycle pathways, with a downregulation of key genes (CDK1, CDK2, CDC20, and PLK1) indicating impaired meiosis in Wugu–Hu rams. In contrast, Hu rams showed minimal transcriptional changes, contrary to the transcriptomic results. The significantly increased apoptosis rate of Wugu–Hu sheep testicular cells (p < 0.05) suggests compensatory or post-transcriptional mechanisms mitigating functional impacts caused by transcriptomic changes. The conclusion is that mild scrotal heat stress affects sperm quality and testicular gene expression. Wugu–Hu rams demonstrate greater transcriptomic sensitivity, but this does not show significant differences in semen quality recovery due to the compensatory mechanism of cell apoptosis. Full article
(This article belongs to the Special Issue Advances in Ovarian and Testicular Physiology)
Show Figures

Graphical abstract

Back to TopTop