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Animals
Special Issues
Diagnosis, Monitoring and Treatment of Physiological Inflammatory in Equids
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Diagnosis, Monitoring and Treatment of Physiological Inflammatory in Equids

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Physiology".

Deadline for manuscript submissions: 15 December 2025 | Viewed by 309

Special Issue Editors

Dr. Francesca Arfuso

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Guest Editor
Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy
Interests: oxidant/antioxidant equilibrium; veterinary physiology; animal welfare; animal management; behavior; health; nutrition and exercise physiology
Special Issues, Collections and Topics in MDPI journals
Dr. Maria Rizzo

E-Mail Website
Guest Editor
Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy
Interests: veterinary physiology; equine welfare; horse management; behavior; health; nutrition and exercise physiology
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Giuseppe Piccione

E-Mail Website
Guest Editor
Department of Veterinary Science, University of Messina, 98168 Messina, Italy
Interests: chronophisiology; thermal biology; equine exercise physiology; transport stress; locomotor activity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Stress can be described as a disruption of homeostasis caused by internal and external factors; what is interesting, therefore, is how stress affects and is still a problematic concept within equine physiology. One of the many effects of the inflammatory reaction to stress conditions is the onset of an acute phase response. If unresolved, stress factors activate, via a cascade system, the hypothalamic–pituitary–adrenal (HPA) axis and the sympathetic nervous system through the production of glucocorticoids and catecholamines, affecting the animal's inflammatory state. Several conditions can cause stress in horses, such as transport, exercise, noisy environments and social isolation. In this vein, we invite you to submit papers that investigate or improve new laboratory methods for diagnosing stress and establish the use of new supplements and/or natural extracts to prevent or treat stressful situations in equids.

Dr. Francesca Arfuso
Dr. Maria Rizzo
Prof. Dr. Giuseppe Piccione
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammation
  • equids
  • stress
  • exercise
  • homeostasis
  • acute phase response

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Published Papers (1 paper)

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Research

11 pages, 1699 KiB  
Communication
The Effect of Ambient Temperature, Relative Humidity, and Temperature–Humidity Index on Stress Hormone and Inflammatory Response in Exercising Adult Standardbred Horses
by Francesca Arfuso, Maria Rizzo, Laura Perillo, Federica Arrigo, Elisabetta Giudice, Giuseppe Piccione, Caterina Faggio and Vincenzo Monteverde
Animals 2025, 15(10), 1436; https://doi.org/10.3390/ani15101436 - 15 May 2025
Viewed by 151
Abstract
In the present study, the changes in the markers of stress and inflammatory responses of 12 Standardbred horses were investigated before and after exercise during late spring and summer. The environmental temperature, relative humidity, and temperature–humidity index (THI) were assessed during this study. [...] Read more.
In the present study, the changes in the markers of stress and inflammatory responses of 12 Standardbred horses were investigated before and after exercise during late spring and summer. The environmental temperature, relative humidity, and temperature–humidity index (THI) were assessed during this study. From horses, blood sampling, measurement of heart and respiratory rate (HR and RR), and measurement of rectal temperature (RT) were performed before exercise (Pre) and within 5 min following the end of the exercise (Post). THI values showed mild stress in June and high stress in July. Direct erythrocyte indices statistically increased after exercise compared to the rest condition (p < 0.05). Higher serum cortisol, α1-, α2-, and β-globulin values were found at Post than at Pre (p < 0.05), whereas lower serum albumin and A/G ratio values were found at Post than at Pre. The HR, RR, and RT statistically increased at Post than at Pre (p < 0.05). The month influenced the values of RR, platelets, cortisol, albumin, α1-, α2-, and β-globulins (p < 0.05). Overall, the results of this study confirmed the well-recognized physiological response of athletic horses to re-establish homeostasis following exercise. Full article
(This article belongs to the Special Issue Diagnosis, Monitoring and Treatment of Physiological Inflammatory in Equids)
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