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Animals
Special Issues
Advances in Exotic Pet Medicine
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Advances in Exotic Pet Medicine

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 1097

Special Issue Editors

Dr. María Ardiaca-García

E-Mail Website
Guest Editor
Hospital Veterinario Medivet 24h Los Sauces, Madrid, Spain
Interests: exotic pet medicine; diagnostic imaging of exotic pets; clinical pathology of exotic pets
Dr. Andrés Montesinos

E-Mail Website
Guest Editor
Centro Veterinario Los Sauces, Madrid, Spain
Interests: exotic pet medicine; pharmacology of exotic pets; surgery of exotic pets; endoscopy of exotic pets

Special Issue Information

Dear Colleagues,

The field of exotic animal medicine has significantly expanded in recent years, contributing a wealth of valuable scientific data. However, due to its vast and complex scope, important gaps remain, and high-quality scientific information is still lacking in many areas and species. In this context, sharing data and research findings is essential for advancing our knowledge and enabling a systematic, evidence-based approach to diseases affecting our exotic patients.

We are pleased to announce the Special Issue of Animals, ‘Advances in Exotic Pet Medicine’. This Special Issue aims to bring together relevant publications on various topics related to exotic pet medicine. We welcome original research articles, comprehensive reviews, case series, and communications that enhance our understanding of this field. The scope of this Special Issue includes any important area of medicine and surgery relating to exotic pets, such as the following:

  • Clinical pathology;
  • Diagnostic imaging;
  • Pharmacology;
  • Surgery;
  • Endoscopy;
  • Pathology;
  • Clinical trials;
  • Case series on a specific disease or syndrome (a minimum of three cases must be included to be considered a case series);
  • Clinical cases (one or two clinical cases reporting novel, unique, or rarely reported clinical entities, unusual presentations of established clinical entities, new clinical diagnostic methods, or novel/previously not described treatments and outcomes).

We very much look forward to receiving your contributions.

Dr. María Ardiaca-García
Dr. Andrés Montesinos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • exotic pet medicine
  • avian medicine
  • reptile medicine
  • small mammals
  • amphibian
  • ornamental fish
  • psittacine
  • passerine
  • rabbit
  • rodents
  • tortoises
  • turtles

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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15 pages, 1140 KiB  
Article
Serum Proteomic Changes in Pet Rabbits with Subclinical and Clinical Encephalitozoonosis in Thailand
by Taksaon Duangurai, Onrapak Reamtong, Tipparat Thiangtrongjit, Siriluk Jala, Peerut Chienwichai and Naris Thengchaisri
Animals 2025, 15(13), 1962; https://doi.org/10.3390/ani15131962 - 3 Jul 2025
Viewed by 425
Abstract
Encephalitozoon cuniculi causes both clinical and subclinical infections in rabbits, complicating a diagnosis due to the limitations of conventional tools like ELISA. This study analyzes serum proteomic profiles across clinical, subclinical, and healthy rabbits to identify discriminatory biomarkers. Serum from 90 pet rabbits [...] Read more.
Encephalitozoon cuniculi causes both clinical and subclinical infections in rabbits, complicating a diagnosis due to the limitations of conventional tools like ELISA. This study analyzes serum proteomic profiles across clinical, subclinical, and healthy rabbits to identify discriminatory biomarkers. Serum from 90 pet rabbits (30 per group) was pooled (10 samples per pool, 3 pools per group) and analyzed using one-dimensional gel electrophoresis and mass spectrometry. The proteomic analysis revealed 109, 98, and 74 proteins expressed in healthy, subclinical, and clinical groups, respectively. Of these, 50, 40, and 33 proteins were unique to the healthy, subclinical, and clinical groups, respectively, with only 10 proteins shared across all. A total of 88 proteins were differentially expressed in infected groups compared to healthy controls. Importantly, 12 proteins were consistently upregulated in both subclinical and clinical infections. These include markers related to the immune response (beta-2-microglobulin, alpha-2-HS-glycoprotein), coagulation (antithrombin-III, alpha-1-antiproteinase S-1), vitamin A transport (retinol-binding proteins), lipid metabolism (apolipoprotein C-III), cytoskeletal regulation (actin-depolymerizing factor), extracellular matrix integrity (fibrillin 2), and oxidative stress (monooxygenase DBH-like 1). Additionally, Gc-globulin and ER lipid-raft-associated 1 were linked to immune modulation and signaling. These findings identify specific serum proteins as promising biomarkers for distinguishing subclinical from clinical encephalitozoonosis in rabbits, enabling an early diagnosis and effective disease monitoring. Full article
(This article belongs to the Special Issue Advances in Exotic Pet Medicine)
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Review

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28 pages, 1220 KiB  
Review
Odontogenic Abscesses in Pet Rabbits: A Comprehensive Review of Pathogenesis, Diagnosis, and Treatment Advances
by Smaranda Crăciun and George Cosmin Nadăş
Animals 2025, 15(13), 1994; https://doi.org/10.3390/ani15131994 - 7 Jul 2025
Viewed by 376
Abstract
Odontogenic abscesses are a frequent and challenging clinical issue in pet rabbits, often requiring a comprehensive diagnostic and therapeutic approach. This review collates current evidence on the etiology, diagnosis, and treatment of rabbit odontogenic abscesses, with a focus on imaging advances, microbial diversity, [...] Read more.
Odontogenic abscesses are a frequent and challenging clinical issue in pet rabbits, often requiring a comprehensive diagnostic and therapeutic approach. This review collates current evidence on the etiology, diagnosis, and treatment of rabbit odontogenic abscesses, with a focus on imaging advances, microbial diversity, and local antimicrobial therapies. Predisposing factors include congenital conformation, inappropriate diet (insufficient abrasiveness, calcium or Vit D deficiencies, etc.), trauma, and neoplasia. Imaging techniques such as CT and cone-beam CT (CBCT) enable early detection and surgical planning, while traditional radiography remains useful in general practice. Treatment includes systemic antibiotics, surgical curettage, and the use of localized delivery systems such as antibiotic-impregnated polymethyl methacrylate (AIPMMA) beads. Adjunctive therapies like Manuka honey are also discussed. Two original heatmaps summarize bacterial prevalence and antimicrobial resistance from six peer-reviewed studies. These visualizations highlight the polymicrobial nature of these infections and the emergence of multidrug-resistant strains. Preventive strategies focus on optimal diet, regular dental checks, and owner education. The review also identifies key gaps in the literature, including the underreporting of anaerobes and lack of standardized treatment protocols. This article aims to support veterinary professionals in delivering evidence-based, individualized care to improve outcomes in rabbits with odontogenic abscesses. Full article
(This article belongs to the Special Issue Advances in Exotic Pet Medicine)
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