Integrated Management and Sustainability of Herbicide Resistance in Crops

A special issue of Agronomy (ISSN 2073-4395). This special issue belongs to the section "Weed Science and Weed Management".

Deadline for manuscript submissions: 30 January 2026 | Viewed by 3492

Special Issue Editors


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Guest Editor
Department Agricultural Chemistry & Soil Sciences, University Cordoba, 14014 Cordoba, Spain
Interests: herbicide cross resistance; herbicide multiple resistance; herbicides; weeds; CytP450; GST; resistant mechanisms
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Guest Editor
Centro de Ciências da Natureza, Universidade Federal de São Carlos, Campus Lagoa do Sino, Buri 18290-000, Brazil
Interests: herbicide cross resistance; herbicide multiple resistance; herbicides; weeds; CytP450; GST; resistant mechanisms
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Agronomy, University of Cordoba, Cordoba, Spain
Interests: agriculture; soil and water conservation; sustainable agriculture; soil fertility; crop production; agricultural development; crop management; fertilizers; conservation agriculture; nutrient management

Special Issue Information

Dear Colleagues,

Herbicide resistance has become a critical challenge for modern agriculture, affecting both crop productivity and sustainability. This phenomenon has increased due to the prolonged and repeated use of certain active substances. Since the introduction of synthetic herbicides in the 1940s, we have observed a steady increase in cases of resistance, especially in recent years, where cross-resistance has gained relevance due to the use of substances with similar mechanisms of action.

This situation underlines the urgent need to investigate and address the problem. Innovative research is currently underway, exploring biotechnological approaches (including the herbicide resistance in crops), agronomic practices, and the use of alternative compounds to mitigate herbicide resistance.

The aim of this Special Issue is to examine the mechanisms underlying herbicide resistance and cross-resistance in diverse crop species, promoting a comprehensive understanding that will contribute to the development of effective management strategies. We invite original articles, reviews, and case studies that address both theoretical and practical aspects of herbicide resistance and its management strategies.

Potential topics include, but are not limited to, the following:

  • Herbicide resistance
  • Cross-resistance
  • European regulations
  • Agricultural sustainability
  • Integrated Weed Management
  • Biotechnology
  • Control strategies
  • Plant health policies
  • Resistant crops
  • Food security

Dr. Antonia María Rojano-Delgado
Dr. Ricardo Alcántara-de la Cruz
Dr. Purificación Fernández García
Guest Editors

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Keywords

  • herbicide resistance
  • herbicide selectivity
  • herbicide efficacy
  • crop tolerance
  • novel herbicidal activity

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Published Papers (2 papers)

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Research

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15 pages, 804 KB  
Article
Weed Seedbank Changes Associated with Temporary Tillage After Long Periods of No-Till
by Fernando Oreja, Marianne Torcat Fuentes, Antonio Barrio, Dario Javier Schiavinato, Virginia Rosso and Elba de la Fuente
Agronomy 2025, 15(6), 1410; https://doi.org/10.3390/agronomy15061410 - 8 Jun 2025
Cited by 1 | Viewed by 1838
Abstract
Long-term no-till systems have led to shifts in weed communities and reduced the effectiveness of herbicide-based control. Occasional tillage is proposed as an alternative strategy to disrupt weed emergence patterns by redistributing seeds within the soil profile. This study aimed to evaluate the [...] Read more.
Long-term no-till systems have led to shifts in weed communities and reduced the effectiveness of herbicide-based control. Occasional tillage is proposed as an alternative strategy to disrupt weed emergence patterns by redistributing seeds within the soil profile. This study aimed to evaluate the impact of occasional tillage on weed seedbank composition and vertical distribution of viable weed seeds and propagules within the soil profile, after more than 20 years of continuous no-till. A paired-plot experiment was conducted in Carlos Casares, Buenos Aires, Argentina, with three replications. Treatments included continuous no-till and occasional tillage (two disk harrow passes in August 2022 and April 2023) combined with three soil depths (0–5, 5–10, and 10–15 cm). Soil samples were collected in spring 2022 and fall 2023, and weed emergence was recorded under semi-controlled conditions. Overall species richness did not differ significantly between tillage treatments but was consistently greater in the upper 0–5 cm soil layer. Weed abundance also declined with depth. Five species, Chenopodium album, Stellaria media, Eleusine indica, Oxybasis macrosperma, and Heliotropium curassavicum, were frequent across treatments. Some species were exclusive to either no-till or tilled plots, for example, Datura ferox, Poa annua, and Veronica peregrina were found only in tilled plots, while Portulaca oleracea, Medicago lupulina, and Trifolium repens were exclusive to no-till plots. These results indicate that occasional tillage alters species composition and vertical seed distribution in the seedbank without significantly reducing total richness or abundance, offering an additional, but not always effective, tool to influence weed community structure in no-till systems. Full article
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Review

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13 pages, 525 KB  
Review
Weed Resistance to Herbicides in Mexico: A Review
by José Alfredo Domínguez-Valenzuela, Candelario Palma-Bautista, Román Eleazar Ruiz-Romero, José G. Vázquez-García, Juan Carlos Delgado-Castillo, Hugo E. Cruz-Hipólito, Ricardo Alcántara-de la Cruz, Rafael De Prado and Guido Plaza
Agronomy 2025, 15(10), 2411; https://doi.org/10.3390/agronomy15102411 - 17 Oct 2025
Viewed by 1020
Abstract
Herbicide resistance in weeds has become a critical challenge in worldwide and Mexican agriculture. Many of these cases involve single, cross and multiple resistance to herbicides that inhibit Acetyl CoA Carboxylase (ACCase), Acetolactate Synthase (ALS), Hydroxyphenyl Pyruvate Dioxygenase (HPPD), and Enolpyruvyl Shikimate Phosphate [...] Read more.
Herbicide resistance in weeds has become a critical challenge in worldwide and Mexican agriculture. Many of these cases involve single, cross and multiple resistance to herbicides that inhibit Acetyl CoA Carboxylase (ACCase), Acetolactate Synthase (ALS), Hydroxyphenyl Pyruvate Dioxygenase (HPPD), and Enolpyruvyl Shikimate Phosphate Synthase (EPSPS) enzymes, as well as auxin mimic herbicides. Documented resistance mechanisms include both target-site resistance (TSR) mutations and various forms of non-target-site resistance (NTSR). In wheat and barley, biotypes with resistance to ACCase, ALS, EPSPS and auxins have been confirmed. Maize–sorghum systems show resistance to ACCase, ALS and EPSPS, and in cotton there are glyphosate-resistant populations of Amaranthus palmeri. Citrus orchards remain the focus of glyphosate resistance. Of concern is the advance of multiple resistance in cereals, exemplified by Avena fatua (ACCase + ALS) and Brassica rapa (EPSPS + ALS + auxin mimics). Unique cases, such as EPSPS resistance in Leptochloa virgata and Bidens pilosa and to HPPD in Setaria adhaerens, are unique to Mexico. These resistance patterns underline the need for robust monitoring and detailed study of molecular and physiological mechanisms, where this has not been done, to inform integrated weed management strategies and curb the spread of weeds. Full article
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