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Most Cited

  • Review
  • Open Access
263 Citations
25,675 Views
25 Pages

Plant Metabolomics: An Overview of the Role of Primary and Secondary Metabolites against Different Environmental Stress Factors

  • Uzma Salam,
  • Shakir Ullah,
  • Zhong-Hua Tang,
  • Ahmed A. Elateeq,
  • Yaseen Khan,
  • Jafar Khan,
  • Asif Khan and
  • Sajid Ali

6 March 2023

Several environmental stresses, including biotic and abiotic factors, adversely affect the growth and development of crops, thereby lowering their yield. However, abiotic factors, e.g., drought, salinity, cold, heat, ultraviolet radiations (UVr), rea...

  • Review
  • Open Access
167 Citations
61,742 Views
27 Pages

29 June 2023

Neuroimaging has revolutionized our understanding of brain function and has become an essential tool for researchers studying neurological disorders. Functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) are two widely used ne...

  • Article
  • Open Access
147 Citations
9,466 Views
16 Pages

Multiple Brain Tumor Classification with Dense CNN Architecture Using Brain MRI Images

  • Osman Özkaraca,
  • Okan İhsan Bağrıaçık,
  • Hüseyin Gürüler,
  • Faheem Khan,
  • Jamil Hussain,
  • Jawad Khan and
  • Umm e Laila

28 January 2023

Brain MR images are the most suitable method for detecting chronic nerve diseases such as brain tumors, strokes, dementia, and multiple sclerosis. They are also used as the most sensitive method in evaluating diseases of the pituitary gland, brain ve...

  • Review
  • Open Access
140 Citations
24,334 Views
32 Pages

Advancement in Solubilization Approaches: A Step towards Bioavailability Enhancement of Poorly Soluble Drugs

  • Lakshmi Kumari,
  • Yash Choudhari,
  • Preeti Patel,
  • Ghanshyam Das Gupta,
  • Dilpreet Singh,
  • Jessica M. Rosenholm,
  • Kuldeep Kumar Bansal and
  • Balak Das Kurmi

27 April 2023

A drug’s aqueous solubility is defined as the ability to dissolve in a particular solvent, and it is currently a major hurdle in bringing new drug molecules to the market. According to some estimates, up to 40% of commercialized products and 70...

  • Review
  • Open Access
138 Citations
28,496 Views
37 Pages

7 February 2024

Drug development is expensive, time-consuming, and has a high failure rate. In recent years, artificial intelligence (AI) has emerged as a transformative tool in drug discovery, offering innovative solutions to complex challenges in the pharmaceutica...

  • Review
  • Open Access
130 Citations
32,674 Views
46 Pages

Short-Chain Fatty Acids and Human Health: From Metabolic Pathways to Current Therapeutic Implications

  • Sonia Facchin,
  • Luisa Bertin,
  • Erica Bonazzi,
  • Greta Lorenzon,
  • Caterina De Barba,
  • Brigida Barberio,
  • Fabiana Zingone,
  • Daria Maniero,
  • Marco Scarpa and
  • Cesare Ruffolo
  • + 2 authors

26 April 2024

The gastrointestinal tract is home to trillions of diverse microorganisms collectively known as the gut microbiota, which play a pivotal role in breaking down undigested foods, such as dietary fibers. Through the fermentation of these food components...

  • Review
  • Open Access
127 Citations
13,025 Views
44 Pages

The Role of Silver Nanoparticles in the Diagnosis and Treatment of Cancer: Are There Any Perspectives for the Future?

  • Peter Takáč,
  • Radka Michalková,
  • Martina Čižmáriková,
  • Zdenka Bedlovičová,
  • Ľudmila Balážová and
  • Gabriela Takáčová

7 February 2023

Cancer is a fatal disease with a complex pathophysiology. Lack of specificity and cytotoxicity, as well as the multidrug resistance of traditional cancer chemotherapy, are the most common limitations that often cause treatment failure. Thus, in recen...

  • Review
  • Open Access
126 Citations
26,752 Views
23 Pages

28 November 2022

The World Health Organization (WHO), in their 2022 report, identified cancer as one of the leading causes of death, accounting for about 16% of deaths worldwide. The Cancer-Moonshot community aims to reduce the cancer death rate by half in the next 2...

  • Review
  • Open Access
107 Citations
9,131 Views
18 Pages

15 February 2023

Diabetic Nephropathy (DN) is a serious complication of type I and II diabetes. It develops from the initial microproteinuria to end-stage renal failure. The main initiator for DN is chronic hyperglycemia. Hyperglycemia (HG) can stimulate the resident...

  • Review
  • Open Access
102 Citations
25,935 Views
20 Pages

The Therapeutic Wound Healing Bioactivities of Various Medicinal Plants

  • Ghosoon Albahri,
  • Adnan Badran,
  • Akram Hijazi,
  • Anis Daou,
  • Elias Baydoun,
  • Mohamad Nasser and
  • Othmane Merah

23 January 2023

The skin serves as the body’s first line of defense, guarding against mechanical, chemical, and thermal damage to the interior organs. It includes a highly developed immune response that serves as a barrier against pathogenic infections. Wound...

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Life - ISSN 2075-1729