Cells | Top Cited Papers in 2022
“Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs”
by Aleksandra Twarda-Clapa, Aleksandra Twarda-Clapa, Aneta M. Białkowska and Maria Koziołkiewicz
Cells 2022, 11(8), 1312; https://doi.org/10.3390/cells11081312
Available online: https://www.mdpi.com/2073-4409/11/8/1312
“Multifactorial Mechanism of Sarcopenia and Sarcopenic Obesity. Role of Physical Exercise, Microbiota and Myokines”
by Jan Bilski, Piotr Pierzchalski, Marian Szczepanik, Joanna Bonior and Jerzy A. Zoladz
Cells 2022, 11(1), 160; https://doi.org/10.3390/cells11010160
Available online: https://www.mdpi.com/2073-4409/11/1/160
“Innate Immune Cell Death in Neuroinflammation and Alzheimer’s Disease”
by Yetirajam Rajesh and Thirumala-Devi Kanneganti
Cells 2022, 11(12), 1885; https://doi.org/10.3390/cells11121885
Available online: https://www.mdpi.com/2073-4409/11/12/1885
“Protective Effects of Curcumin in Cardiovascular Diseases—Impact on Oxidative Stress and Mitochondria”
by Fiona Frederike Cox, Angelina Misiou, Annika Vierkant, Niloofar Ale-Agha, Maria Grandoch, Judith Haendeler and Joachim Altschmied
Cells 2022, 11(3), 342; https://doi.org/10.3390/cells11030342
Available online: https://www.mdpi.com/2073-4409/11/3/342
“Causes of and Molecular Targets for the Treatment of Intervertebral Disc Degeneration: A Review”
by Takashi Ohnishi, Norimasa Iwasaki and Hideki Sudo
Cells 2022, 11(3), 394; https://doi.org/10.3390/cells11030394
Available online: https://www.mdpi.com/2073-4409/11/3/394
“Into the Tissues: Extracellular Matrix and Its Artificial Substitutes: Cell Signalling Mechanisms“
by Aleksandra Bandzerewicz and Agnieszka Gadomska-Gajadhur
Cells 2022, 11(5), 914; https://doi.org/10.3390/cells11050914
Available online: https://www.mdpi.com/2073-4409/11/5/914
“The Role of the Immune System in the Development of Endometriosis“
by Monika Abramiuk, Ewelina Grywalska, Paulina Małkowska, Olga Sierawska, Rafał Hrynkiewicz and Niedźwiedzka-Rystwej
Cells 2022, 11(13), 2028; https://doi.org/10.3390/cells11132028
Available online: https://www.mdpi.com/2073-4409/11/13/2028
“Stem Cells and Angiogenesis: Implications and Limitations in Enhancing Chronic Diabetic Foot Ulcer Healing“
by Vikrant Rai, Rebecca Moellmer and Devendra K. Agrawal
Cells 2022, 11(15), 2287; https://doi.org/10.3390/cells11152287
Available online: https://www.mdpi.com/2073-4409/11/15/2287
“Cardiovascular Inflammaging: Mechanisms and Translational Aspects“
by Maria Luisa Barcena, Muhammad Aslam, Sofya Pozdniakova, Kristina Norman and Yury Ladilov
Cells 2022, 11(6), 1010; https://doi.org/10.3390/cells11061010
Available online: https://www.mdpi.com/2073-4409/11/6/1010
“One-Carbon Metabolism: Pulling the Strings behind Aging and Neurodegeneration“
by Eirini Lionaki, Christina Ploumi and Nektarios Tavernarakis
Cells 2022, 11(2), 214; https://doi.org/10.3390/cells11020214
Available online: https://www.mdpi.com/2073-4409/11/2/214
“Tendon Immune Regeneration: Insights on the Synergetic Role of Stem and Immune Cells during Tendon Regeneration“
by Valentina Russo, Mohammad El Khatib, Giuseppe Prencipe, Maria Rita Citeroni, Melisa Faydaver, Annunziata Mauro, Paolo Berardinelli, Adrián Cerveró-Varona, Arlette A. Haidar-Montes, Maura Turriani et al.
Cells 2022, 11(3), 434; https://doi.org/10.3390/cells11030434
Available online: https://www.mdpi.com/2073-4409/11/3/434
“Necroptosis and Prostate Cancer: Molecular Mechanisms and Therapeutic Potential“
by Giovanni Luca Beretta and Nadia Zaffaroni
Cells 2022, 11(7), 1221; https://doi.org/10.3390/cells11071221
Available online: https://www.mdpi.com/2073-4409/11/7/1221
“Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD“
by Luca Giordano, Alyssa D. Gregory, Mireia Pérez Verdaguer, Sarah A. Ware, Hayley Harvey, Evan DeVallance, Tomasz Brzoska, Prithu Sundd, Yingze Zhang, Frank C. Sciurba et al.
Cells 2022, 11(3), 369; https://doi.org/10.3390/cells11030369
Available online: https://www.mdpi.com/2073-4409/11/3/369
“Glucose Regulates m6A Methylation of RNA in Pancreatic Islets”
by Florine Bornaque, Clément Philippe Delannoy, Emilie Courty, Nabil Rabhi, Charlène Carney, Laure Rolland, Maeva Moreno, Xavier Gromada, Cyril Bourouh, Pauline Petit et al.
Cells 2022, 11(2), 291; https://doi.org/10.3390/cells11020291
Available online: https://www.mdpi.com/2073-4409/11/2/291
“High-Fat Diet-Induced Dysregulation of Immune Cells Correlates with Macrophage Phenotypes and Chronic Inflammation in Adipose Tissue”
by Sonia Kiran, Ahmed Rakib, Sunitha Kodidela, Santosh Kumar and Udai P. Singh
Cells 2022, 11(8), 1327; https://doi.org/10.3390/cells11081327
Available online: https://www.mdpi.com/2073-4409/11/8/1327
“Anticoagulants: A Short History, Their Mechanism of Action, Pharmacology, and Indications”
by Marco Heestermans, Géraldine Poenou, Hind Hamzeh-Cognasse, Fabrice Cognasse and Laurent Bertoletti
Cells 2022, 11(20), 3214; https://doi.org/10.3390/cells11203214
Available online: https://www.mdpi.com/2073-4409/11/20/3214
“Probiotics in the Prevention of the Calcium Oxalate Urolithiasis”
by Paulina Wigner, Michał Bijak and Joanna Saluk-Bijak
Cells 2022, 11(2), 284; https://doi.org/10.3390/cells11020284
Available online: https://www.mdpi.com/2073-4409/11/2/284
“The Future of the COVID-19 Pandemic: How Good (or Bad) Can the SARS-CoV2 Spike Protein Get?”
by Matthew A. Nugent
Cells 2022, 11(5), 855; https://doi.org/10.3390/cells11050855
Available online: https://www.mdpi.com/2073-4409/11/5/855
“Dance of The Golgi: Understanding Golgi Dynamics in Cancer Metastasis”
by Rakhee Bajaj, Amanda N. Warner, Jared F. Fradette and Don L. Gibbons
Cells 2022, 11(9), 1484; https://doi.org/10.3390/cells11091484
Available online: https://www.mdpi.com/2073-4409/11/9/1484
“Endothelial Progenitor Cells as Biomarkers of Cardiovascular Pathologies: A Narrative Review”
by Paul Philipp Heinisch, Corina Bello, Maximilian Y. Emmert, Thierry Carrel, Martina Dreßen, Jürgen Hörer, Bernhard Winkler and Markus M. Luedi
Cells 2022, 11(10), 1678; https://doi.org/10.3390/cells11101678
Available online: https://www.mdpi.com/2073-4409/11/10/1678
“Transient Exposure of Endothelial Cells to Doxorubicin Leads to Long-Lasting Vascular Endothelial Growth Factor Receptor 2 Downregulation”
by Silvia Graziani, Luca Scorrano and Giovanna Pontarin
Cells 2022, 11(2), 210; https://doi.org/10.3390/cells11020210
Available online: https://www.mdpi.com/2073-4409/11/2/210
“Mesenchymal Stromal/Stem Cells and Their Products as a Therapeutic Tool to Advance Lung Transplantation”
by Vitale Miceli and Alessandro Bertani
Cells 2022, 11(5), 826; https://doi.org/10.3390/cells11050826
Available online: https://www.mdpi.com/2073-4409/11/5/826
“Pyroptosis and Its Role in SARS-CoV-2 Infection”
by Zsofia Agnes Bittner, Markus Schrader, Shilpa Elizabeth George and Ralf Amann
Cells 2022, 11(10), 1717; https://doi.org/10.3390/cells11101717
Available online: https://www.mdpi.com/2073-4409/11/10/1717
“The H+ Transporter SLC4A11: Roles in Metabolism, Oxidative Stress and Mitochondrial Uncoupling”
by Joseph A. Bonanno, Raji Shyam, Moonjung Choi and Diego G. Ogando
Cells 2022, 11(2), 197; https://doi.org/10.3390/cells11020197
Available online: https://www.mdpi.com/2073-4409/11/2/197
“Molecular Mechanisms of Exercise and Healthspan”
by Yuntian Guan and Zhen Yan
Cells 2022, 11(5), 872; https://doi.org/10.3390/cells11050872
Available online: https://www.mdpi.com/2073-4409/11/5/872
“Modulating the Ubiquitin–Proteasome System: A Therapeutic Strategy for Autoimmune Diseases”
by Dhananjay Yadav, Ji Yeon Lee, Nidhi Puranik, Pallavi S. Chauhan, Vishal Chavda, Jun-O. Jin and Peter C. W. Lee
Cells 2022, 11(7), 1093; https://doi.org/10.3390/cells11071093
Available online: https://www.mdpi.com/2073-4409/11/7/1093
“Understanding Molecular Mechanisms of Phenotype Switching and Crosstalk with TME to Reveal New Vulnerabilities of Melanoma”
by Ahmad Najem, Laura Soumoy, Malak Sabbah, Mohammad Krayem, Ahmad Awada, Fabrice Journe and Ghanem E. Ghanem
Cells 2022, 11(7), 1157; https://doi.org/10.3390/cells11071157
Available online: https://www.mdpi.com/2073-4409/11/7/1157
“Verteporfin Inhibits the Progression of Spontaneous Osteosarcoma Caused by Trp53 and Rb1 Deficiency in Ctsk-Expressing Cells via Impeding Hippo Pathway”
by Yang Li, Shuting Yang and Shuying Yang
Cells 2022, 11(8), 1361; https://doi.org/10.3390/cells11081361
Available online: https://www.mdpi.com/2073-4409/11/8/1361
“Role of Intestinal Dysbiosis and Nutrition in Rheumatoid Arthritis”
by Malavikalakshmi Attur, Jose U Scher, Steven B. Abramson and Mukundan Attur
Cells 2022, 11(15), 2436; https://doi.org/10.3390/cells11152436
Available online: https://www.mdpi.com/2073-4409/11/15/2436
“Apple Derived Exosomes Improve Collagen Type I Production and Decrease MMPs during Aging of the Skin through Downregulation of the NF-κB Pathway as Mode of Action”
by Martina Trentini, Ilaria Zanolla, Federica Zanotti, Elena Tiengo, Danilo Licastro, Simeone Dal Monego, Luca Lovatti and Barbara Zavan
Cells 2022, 11(24), 3950; https://doi.org/10.3390/cells11243950
Available online: https://www.mdpi.com/2073-4409/11/24/3950
“Regulation of Mitochondrial Hydrogen Peroxide Availability by Protein S-glutathionylation”
by Ryan J. Mailloux, Cathryn Grayson and Olivia Koufos
Cells 2023, 12(1), 107; https://doi.org/10.3390/cells12010107
Available online: https://www.mdpi.com/2073-4409/12/1/107
“Transcriptional Heterogeneity and the Microbiome of Cutaneous T-Cell Lymphoma”
by Philipp Licht and Volker Mailander
Cells 2022, 11(3), 328; https://doi.org/10.3390/cells11030328
Available online: https://www.mdpi.com/2073-4409/11/3/328
“Cytochrome c Oxidase Inhibition by ATP Decreases Mitochondrial ROS Production”
by Rabia Ramzan, Amalia M. Dolga, Susanne Michels, Petra Weber, Carsten Culmsee, Ardawan J. Rastan and Sebastian Vogt
Cells 2022, 11(6), 992; https://doi.org/10.3390/cells11060992
Available online: https://www.mdpi.com/2073-4409/11/6/992
“The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved”
by Laura Giusti, Marta Tesi, Federica Ciregia, Lorella Marselli, Lorenzo Zallocco, Mara Suleiman, Carmela De Luca, Silvia Del Guerra, Mariachiara Zuccarini, Marco Trerotola et al.
Cells 2022, 11(15), 2465; https://doi.org/10.3390/cells11152465
Available online: https://www.mdpi.com/2073-4409/11/15/2465
“Neurodegenerative Disease-Associated TDP-43 Fragments Are Extracellularly Secreted with CASA Complex Proteins”
Elena Casarotto, Daisy Sproviero, Eleonora Corridori, Maria Cristina Gagliani, Marta Cozzi, Marta Chierichetti, Riccardo Cristofani, Veronica Ferrari, Mariarita Galbiati, Francesco Mina et al.
Cells 2022, 11(3), 516; https://doi.org/10.3390/cells11030516
Available online: https://www.mdpi.com/2073-4409/11/3/516
“The Cell Membrane of a Novel Rhizobium phaseoli Strain Is the Crucial Target for Aluminium Toxicity and Tolerance”
by Clabe Wekesa, John O. Muoma, Michael Reichelt, George O. Asudi, Alexandra C. U. Furch and Ralf Oelmüller
Cells 2022, 11(5), 873; https://doi.org/10.3390/cells11050873
Available online: https://www.mdpi.com/2073-4409/11/5/873
“Senescence-Associated Cell Transition and Interaction (SACTAI): A Proposed Mechanism for Tissue Aging, Repair, and Degeneration”
by Yajun Liu, Jonah Schwam and Qian Chen
Cells 2022, 11(7), 1089; https://doi.org/10.3390/cells11071089
Available online: https://www.mdpi.com/2073-4409/11/7/1089
“Mesenchymal Stromal Cell-Derived Extracellular Vesicles for Neonatal Lung Disease: Tiny Particles, Major Promise, Rigorous Requirements for Clinical Translation”
by Flore Lesage and Bernard Thébaud
Cells 2022, 11(7), 1176; https://doi.org/10.3390/cells11071176
Available online: https://www.mdpi.com/2073-4409/11/7/1176
“The Cytoskeleton Effectors Rho-Kinase (ROCK) and Mammalian Diaphanous-Related (mDia) Formin Have Dynamic Roles in Tumor Microtube Formation in Invasive Glioblastoma Cells”
by Kathryn N. Becker, Krista M. Pettee, Amanda Sugrue, Kevin A. Reinard, Jason L. Schroeder and Kathryn M. Eisenmann
Cells 2022, 11(9), 1559; https://doi.org/10.3390/cells11091559
Available online: https://www.mdpi.com/2073-4409/11/9/1559
“Reactive Oxygen Species in Regulating Lymphangiogenesis and Lymphatic Function”
by Bhupesh Singla, Ravi Varma Aithabathula, Sonia Kiran, Shweta Kapil, Santosh Kumar and Udai P. Singh
Cells 2022, 11(11), 1750; https://doi.org/10.3390/cells11111750
Available online: https://www.mdpi.com/2073-4409/11/11/1750
“Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders”
by Cláudia M. Deus, Henrique Tavares, Margarida Beatriz, Sandra Mota and Carla Lopes
Cells 2022, 11(15), 2364; https://doi.org/10.3390/cells11152364
Available online: https://www.mdpi.com/2073-4409/11/15/2364
“Akkermansia muciniphila Reduces Peritonitis and Improves Intestinal Tissue Wound Healing after a Colonic Transmural Defect by a MyD88-Dependent Mechanism”
by Radu Bachmann, Matthias Van Hul, Pamela Baldin, Daniel Léonard, Nathalie M. Delzenne, Clara Belzer, Janneke P. Ouwerkerk, Dirk Repsilber, Ignacio Rangel and Alex Kartheuser
Cells 2022, 11(17), 2666; https://doi.org/10.3390/cells11172666
Available online: https://www.mdpi.com/2073-4409/11/17/2666
“STAT3 and Its Pathways’ Dysregulation—Underestimated Role in Urological Tumors“
by Maciej Golus, Piotr Bugajski, Joanna Chorbińska, Wojciech Krajewski, Artur Lemiński, Jolanta Saczko, Julita Kulbacka, Tomasz Szydełko and Bartosz Małkiewicz
Cells 2022, 11(19), 3024; https://doi.org/10.3390/cells11193024
Available online: https://www.mdpi.com/2073-4409/11/19/3024
“Bone Marrow Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles Promote Corneal Wound Repair by Regulating Inflammation and Angiogenesis”
by Gabriele Saccu, Valeria Menchise, Chiara Gai, Marina Bertolin, Stefano Ferrari, Cristina Giordano, Marta Manco, Walter Dastrù, Emanuela Tolosano and Benedetta Bussolati
Cells 2022, 11(23), 3892; https://doi.org/10.3390/cells11233892
Available online: https://www.mdpi.com/2073-4409/11/23/3892
“Enhancing In Vitro Production of the Tree Fern Cyathea delgadii and Modifying Secondary Metabolite Profiles by LED Lighting”
by Wojciech Tomaszewicz, Monika Cioć, Katarzyna Dos Santos Szewczyk, Małgorzata Grzyb, Wioleta Pietrzak, Bożena Pawłowska and Anna Mikuła
Cells 2022, 11(3), 486; https://doi.org/10.3390/cells11030486
Available online: https://www.mdpi.com/2073-4409/11/3/486
“C53 Interacting with UFM1-Protein Ligase 1 Regulates Microtubule Nucleation in Response to ER Stress”
by Anastasiya Klebanovych, Stanislav Vinopal, Eduarda Dráberová, Vladimíra Sládková, Tetyana Sulimenko, Vadym Sulimenko, Věra Vosecká, Libor Macůrek, Agustin Legido and Pavel Dráber
Cells 2022, 11(3), 555; https://doi.org/10.3390/cells11030555
Available online: https://www.mdpi.com/2073-4409/11/3/555
“Targeting Protein O-GlcNAcylation, a Link between Type 2 Diabetes Mellitus and Inflammatory Disease”
by Israel Olapeju Bolanle and Timothy M. Palmer
Cells 2022, 11(4), 705; https://doi.org/10.3390/cells11040705
Available online: https://www.mdpi.com/2073-4409/11/4/705
“How Cargo Identity Alters the Uptake of Cell-Penetrating Peptide (CPP)/Cargo Complexes: A Study on the Effect of Net Cargo Charge and Length”
By Hannah C. Hymel, Alireza Rahnama, Olivia M. Sanchez, Dong Liu, Ted J. Gauthier and Adam T. Melvin
Cells 2022, 11(7), 1195; https://doi.org/10.3390/cells11071195
Available online: https://www.mdpi.com/2073-4409/11/7/1195
“Human Platelet-Rich Plasma Facilitates Angiogenesis to Restore Impaired Uterine Environments with Asherman’s Syndrome for Embryo Implantation and Following Pregnancy in Mice”
by Min Kyoung Kim, Jung Ah Yoon, Sook Young Yoon, Mira Park, Woo Sik Lee, Sang Woo Lyu and Haengseok Song
Cells 2022, 11(9), 1549; https://doi.org/10.3390/cells11091549
Available online: https://www.mdpi.com/2073-4409/11/9/1549
“Targeting Acid Ceramidase Inhibits Glioblastoma Cell Migration through Decreased AKT Signaling”
by Cyntanna C. Hawkins, Amber B. Jones, Emily R. Gordon, Sarah E. Williford, Yuvika Harsh, Julia K. Ziebro, Catherine J. Landis, Sajina Gc, David K. Crossman and Sara J. Cooper
Cells 2022, 11(12), 1873; https://doi.org/10.3390/cells11121873
Available online: https://www.mdpi.com/2073-4409/11/12/1873